Affinity Data by PubMed id=16647258

PubMed code 16647258

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50150211 (3-(2,4-Difluoro-phenoxy)-2-(4-methanesulfonyl-phen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50150226 (3-(4-Bromo-2-fluoro-phenoxy)-2-(4-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50150185 (3-(4-Chloro-2-fluoro-phenoxy)-2-(4-methanesulfonyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50186097 ((R)-3-(4-bromo-2-fluorophenoxy)-6-methyl-2-(4-(met...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50186096 ((R)-3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(me...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50186097 ((R)-3-(4-bromo-2-fluorophenoxy)-6-methyl-2-(4-(met...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50186096 ((R)-3-(4-chloro-2-fluorophenoxy)-6-methyl-2-(4-(me...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22369 (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50072064 (5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50186095 ((R)-3-(2,4-difluorophenoxy)-6-methyl-2-(4-(methyls...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50186095 ((R)-3-(2,4-difluorophenoxy)-6-methyl-2-(4-(methyls...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood				Bioorg Med Chem Lett 16: 3605-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.101 BindingDB Entry DOI: 10.7270/Q22B8XND
Rhône-Poulenc Rorer Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%