Affinity Data by PubMed id=16682195

PubMed code 16682195

Found 37 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186512 (CHEMBL377810 \| benzyl 6-benzyl-2-hydroxy-5-oxo-5,6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186512 (CHEMBL377810 \| benzyl 6-benzyl-2-hydroxy-5-oxo-5,6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186500 (1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186507 ((5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone \| CHEMB...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186507 ((5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone \| CHEMB...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186500 (1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186513 (CHEMBL212569 \| benzyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186510 ((2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone \| CHE...) Show SMILES CO[C@@H]1CCCC(=O)[C@H]1OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186504 (2-benzyl-1-(phenylsulfonyl)-1,2-dihydropyridin-3(6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186506 ((5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186502 (CHEMBL210178 \| methyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES COC(=O)N1CC=CC(=O)C1Cc1ccccc1 \|c:6\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186513 (CHEMBL212569 \| benzyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186502 (CHEMBL210178 \| methyl 6-benzyl-5-oxo-5,6-dihydropy...) Show SMILES COC(=O)N1CC=CC(=O)C1Cc1ccccc1 \|c:6\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186506 ((5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186504 (2-benzyl-1-(phenylsulfonyl)-1,2-dihydropyridin-3(6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186510 ((2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone \| CHE...) Show SMILES CO[C@@H]1CCCC(=O)[C@H]1OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186508 ((5R,6S)-5-(benzyloxy)-6-methoxycyclohex-2-enone \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186508 ((5R,6S)-5-(benzyloxy)-6-methoxycyclohex-2-enone \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186509 ((2S,3R)-3-(benzyloxy)-5-hydroxy-2-methoxycyclohexa...) Show SMILES CO[C@H]1[C@@H](CC(O)CC1=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186511 ((2S,3R)-3-(benzyloxy)-2-methoxycyclohexanone \| CHE...) Show SMILES CO[C@H]1[C@@H](CCCC1=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186505 (CHEMBL211287 \| methyl 2-benzyl-3-oxopiperidine-1-c...) Show SMILES COC(=O)N1CCCC(=O)C1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186499 (CHEMBL377425 \| benzyl 2-benzyl-3-hydroxypiperidine...) Show SMILES OC1CCCN(C1Cc1ccccc1)C(=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186517 (CHEMBL209225 \| methyl 2-benzyl-3-hydroxypiperidine...) Show SMILES COC(=O)N1CCCC(O)C1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186516 (CHEMBL378711 \| benzyl 2-benzyl-3-oxopiperidine-1-c...) Show SMILES O=C(OCc1ccccc1)N1CCCC(=O)C1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186515 ((2S,3R)-2-hydroxy-3-methoxycyclohexanone \| CHEMBL3...) Show SMILES CO[C@@H]1CCCC(=O)[C@H]1O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186501 ((2S,3R)-2-(benzyloxy)-5-hydroxy-3-methoxycyclohexa...) Show SMILES CO[C@@H]1CC(O)CC(=O)[C@H]1OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186517 (CHEMBL209225 \| methyl 2-benzyl-3-hydroxypiperidine...) Show SMILES COC(=O)N1CCCC(O)C1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186515 ((2S,3R)-2-hydroxy-3-methoxycyclohexanone \| CHEMBL3...) Show SMILES CO[C@@H]1CCCC(=O)[C@H]1O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186514 ((2S,3R)-3-hydroxy-2-methoxycyclohexanone \| CHEMBL2...) Show SMILES CO[C@H]1[C@H](O)CCCC1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186503 ((2S,3R)-2,3-bis(benzyloxy)cyclohexanone \| CHEMBL20...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186509 ((2S,3R)-3-(benzyloxy)-5-hydroxy-2-methoxycyclohexa...) Show SMILES CO[C@H]1[C@@H](CC(O)CC1=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186503 ((2S,3R)-2,3-bis(benzyloxy)cyclohexanone \| CHEMBL20...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186505 (CHEMBL211287 \| methyl 2-benzyl-3-oxopiperidine-1-c...) Show SMILES COC(=O)N1CCCC(=O)C1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186511 ((2S,3R)-3-(benzyloxy)-2-methoxycyclohexanone \| CHE...) Show SMILES CO[C@H]1[C@@H](CCCC1=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186514 ((2S,3R)-3-hydroxy-2-methoxycyclohexanone \| CHEMBL2...) Show SMILES CO[C@H]1[C@H](O)CCCC1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186499 (CHEMBL377425 \| benzyl 2-benzyl-3-hydroxypiperidine...) Show SMILES OC1CCCN(C1Cc1ccccc1)C(=O)OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2 (Homo sapiens (Human))	BDBM50186501 ((2S,3R)-2-(benzyloxy)-5-hydroxy-3-methoxycyclohexa...) Show SMILES CO[C@@H]1CC(O)CC(=O)[C@H]1OCc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 42				Bioorg Med Chem Lett 16: 3813-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.025 BindingDB Entry DOI: 10.7270/Q2VM4BVF
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%