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PubMed code 16686532

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186604
PNG
(4-((N-(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl...)
Show SMILES CN(CCCc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)Cc1no[n+]([O-])c1C(N)=O
Show InChI InChI=1S/C22H34N4O4/c1-21(2,3)15-11-14(12-16(19(15)27)22(4,5)6)9-8-10-25(7)13-17-18(20(23)28)26(29)30-24-17/h11-12,27H,8-10,13H2,1-7H3,(H2,23,28)
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n/an/an/an/a 7.40E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186606
PNG
(3-(4-hydroxyphenyl)prop-1,2-diyl dinitrate | CHEMB...)
Show SMILES Oc1ccc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc1
Show InChI InChI=1S/C9H10N2O6/c12-9-3-1-7(2-4-9)5-8(10(13)14)6-17-11(15)16/h1-4,8,12H,5-6H2
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n/an/an/an/a 130n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186603
PNG
(4-((N-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)...)
Show SMILES CN(Cc1no[n+]([O-])c1C(N)=O)CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
Show InChI InChI=1S/C19H26N4O5/c1-10-11(2)17-13(12(3)16(10)24)6-7-19(4,27-17)9-22(5)8-14-15(18(20)25)23(26)28-21-14/h24H,6-9H2,1-5H3,(H2,20,25)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156310
PNG
(4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)phen...)
Show SMILES Oc1ccc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C17H16N2O6S/c20-14-10-8-13(9-11-14)5-4-12-24-16-17(19(21)25-18-16)26(22,23)15-6-2-1-3-7-15/h1-3,6-11,20H,4-5,12H2
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186613
PNG
(4-hydroxymethyl-2-oxy-furazan-3-carboxylic acid am...)
Show SMILES NC(=O)c1c(CO)no[n+]1[O-]
Show InChI InChI=1S/C4H5N3O4/c5-4(9)3-2(1-8)6-11-7(3)10/h8H,1H2,(H2,5,9)
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n/an/an/an/a 6.30E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186607
PNG
(4-dimethylaminomethyl-2-oxy-furazan-3-carboxylic a...)
Show SMILES CN(C)Cc1no[n+]([O-])c1C(N)=O
Show InChI InChI=1S/C6H10N4O3/c1-9(2)3-4-5(6(7)11)10(12)13-8-4/h3H2,1-2H3,(H2,7,11)
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n/an/an/an/a 3.10E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186612
PNG
(1,2-bis-nitrooxy-propane | CHEMBL206527)
Show SMILES CC(CO[N+]([O-])=O)O[N+]([O-])=O
Show InChI InChI=1S/C3H6N2O6/c1-3(11-5(8)9)2-10-4(6)7/h3H,2H2,1H3
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n/an/an/an/a 240n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186604
PNG
(4-((N-(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl...)
Show SMILES CN(CCCc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C)Cc1no[n+]([O-])c1C(N)=O
Show InChI InChI=1S/C22H34N4O4/c1-21(2,3)15-11-14(12-16(19(15)27)22(4,5)6)9-8-10-25(7)13-17-18(20(23)28)26(29)30-24-17/h11-12,27H,8-10,13H2,1-7H3,(H2,23,28)
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156308
PNG
(4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...)
Show SMILES CC(C)(C)c1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C25H32N2O6S/c1-24(2,3)19-15-17(16-20(21(19)28)25(4,5)6)11-10-14-32-22-23(27(29)33-26-22)34(30,31)18-12-8-7-9-13-18/h7-9,12-13,15-16,28H,10-11,14H2,1-6H3
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156309
PNG
(2,6-Di-tert-butyl-4-(3-nitrooxy-propyl)-phenol | 3...)
Show SMILES CC(C)(C)c1cc(CCCO[N+]([O-])=O)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C17H27NO4/c1-16(2,3)13-10-12(8-7-9-22-18(20)21)11-14(15(13)19)17(4,5)6/h10-11,19H,7-9H2,1-6H3
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n/an/an/an/a 4.00E+4n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186608
PNG
(3-((4-hydroxy-3,5-dimethoxy)phenyl)prop-1,2-diyl d...)
Show SMILES COc1cc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc(OC)c1O
Show InChI InChI=1S/C11H14N2O8/c1-19-9-4-7(5-10(20-2)11(9)14)3-8(12(15)16)6-21-13(17)18/h4-5,8,14H,3,6H2,1-2H3
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n/an/an/an/a 4.90E+4n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186610
PNG
(3-((4-hydroxy-3,5-di-tert-butyl)phenyl)prop-1,2-di...)
Show SMILES CC(C)(C)c1cc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C17H26N2O6/c1-16(2,3)13-8-11(9-14(15(13)20)17(4,5)6)7-12(18(21)22)10-25-19(23)24/h8-9,12,20H,7,10H2,1-6H3
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n/an/an/an/a 3.30E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186608
PNG
(3-((4-hydroxy-3,5-dimethoxy)phenyl)prop-1,2-diyl d...)
Show SMILES COc1cc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc(OC)c1O
Show InChI InChI=1S/C11H14N2O8/c1-19-9-4-7(5-10(20-2)11(9)14)3-8(12(15)16)6-21-13(17)18/h4-5,8,14H,3,6H2,1-2H3
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156307
PNG
(3-(4-hydroxyphenyl)propyl nitrate | 4-(3-Nitrooxy-...)
Show SMILES Oc1ccc(CCCO[N+]([O-])=O)cc1
Show InChI InChI=1S/C9H11NO4/c11-9-5-3-8(4-6-9)2-1-7-14-10(12)13/h3-6,11H,1-2,7H2
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n/an/an/an/a 1.00E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156306
PNG
(1-nitrooxy-propane | CHEMBL188554)
Show SMILES CCCO[N+]([O-])=O
Show InChI InChI=1S/C3H7NO3/c1-2-3-7-4(5)6/h2-3H2,1H3
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n/an/an/an/a 4.10E+4n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156308
PNG
(4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...)
Show SMILES CC(C)(C)c1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C25H32N2O6S/c1-24(2,3)19-15-17(16-20(21(19)28)25(4,5)6)11-10-14-32-22-23(27(29)33-26-22)34(30,31)18-12-8-7-9-13-18/h7-9,12-13,15-16,28H,10-11,14H2,1-6H3
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n/an/an/an/a 4.80E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156303
PNG
(2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8...)
Show SMILES Cc1c(C)c2OC(C)(COc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)CCc2c(C)c1O
Show InChI InChI=1S/C22H24N2O7S/c1-13-14(2)19-17(15(3)18(13)25)10-11-22(4,30-19)12-29-20-21(24(26)31-23-20)32(27,28)16-8-6-5-7-9-16/h5-9,25H,10-12H2,1-4H3
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186605
PNG
(4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...)
Show SMILES COc1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(OC)c1O
Show InChI InChI=1S/C19H20N2O8S/c1-26-15-11-13(12-16(27-2)17(15)22)7-6-10-28-18-19(21(23)29-20-18)30(24,25)14-8-4-3-5-9-14/h3-5,8-9,11-12,22H,6-7,10H2,1-2H3
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186605
PNG
(4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)-2,6...)
Show SMILES COc1cc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc(OC)c1O
Show InChI InChI=1S/C19H20N2O8S/c1-26-15-11-13(12-16(27-2)17(15)22)7-6-10-28-18-19(21(23)29-20-18)30(24,25)14-8-4-3-5-9-14/h3-5,8-9,11-12,22H,6-7,10H2,1-2H3
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156310
PNG
(4-(3-(3-benzenesulfonylfuroxan-4-yloxy)propyl)phen...)
Show SMILES Oc1ccc(CCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C17H16N2O6S/c20-14-10-8-13(9-11-14)5-4-12-24-16-17(19(21)25-18-16)26(22,23)15-6-2-1-3-7-15/h1-3,6-11,20H,4-5,12H2
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156303
PNG
(2-(3-benzenesulfonylfuroxan-4-yloxymethyl)-2,5,7,8...)
Show SMILES Cc1c(C)c2OC(C)(COc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)CCc2c(C)c1O
Show InChI InChI=1S/C22H24N2O7S/c1-13-14(2)19-17(15(3)18(13)25)10-11-22(4,30-19)12-29-20-21(24(26)31-23-20)32(27,28)16-8-6-5-7-9-16/h5-9,25H,10-12H2,1-4H3
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Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156305
PNG
(2,5,7,8-Tetramethyl-2-(3-nitrooxy-propoxymethyl)-c...)
Show SMILES Cc1c(C)c2OC(C)(COCCCO[N+]([O-])=O)CCc2c(C)c1O
Show InChI InChI=1S/C17H25NO6/c1-11-12(2)16-14(13(3)15(11)19)6-7-17(4,24-16)10-22-8-5-9-23-18(20)21/h19H,5-10H2,1-4H3
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UniProtKB/SwissProt

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n/an/an/an/a 1.00E+4n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186606
PNG
(3-(4-hydroxyphenyl)prop-1,2-diyl dinitrate | CHEMB...)
Show SMILES Oc1ccc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc1
Show InChI InChI=1S/C9H10N2O6/c12-9-3-1-7(2-4-9)5-8(10(13)14)6-17-11(15)16/h1-4,8,12H,5-6H2
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n/an/an/an/a 6.50E+4n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186603
PNG
(4-((N-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)...)
Show SMILES CN(Cc1no[n+]([O-])c1C(N)=O)CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
Show InChI InChI=1S/C19H26N4O5/c1-10-11(2)17-13(12(3)16(10)24)6-7-19(4,27-17)9-22(5)8-14-15(18(20)25)23(26)28-21-14/h24H,6-9H2,1-5H3,(H2,20,25)
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n/an/an/an/a 1.90E+4n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips in presence of 1 uM ODQ

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156305
PNG
(2,5,7,8-Tetramethyl-2-(3-nitrooxy-propoxymethyl)-c...)
Show SMILES Cc1c(C)c2OC(C)(COCCCO[N+]([O-])=O)CCc2c(C)c1O
Show InChI InChI=1S/C17H25NO6/c1-11-12(2)16-14(13(3)15(11)19)6-7-17(4,24-16)10-22-8-5-9-23-18(20)21/h19H,5-10H2,1-4H3
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n/an/an/an/a 1.20E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50186611
PNG
(3-(4-hydroxy-3,5-dimethoxyphenyl)propyl nitrate | ...)
Show SMILES COc1cc(CCCO[N+]([O-])=O)cc(OC)c1O
Show InChI InChI=1S/C11H15NO6/c1-16-9-6-8(4-3-5-18-12(14)15)7-10(17-2)11(9)13/h6-7,13H,3-5H2,1-2H3
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n/an/an/an/a 4.30E+3n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Rattus norvegicus (Rat))		BDBM50156304
PNG
(3-benzenesulfonyl-4-ethoxy-furazan 2-oxide | 4-eth...)
Show SMILES CCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C10H10N2O5S/c1-2-16-9-10(12(13)17-11-9)18(14,15)8-6-4-3-5-7-8/h3-7H,2H2,1H3
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n/an/an/an/a 12n/an/an/an/a



Università degli Studi di Torino

Curated by ChEMBL


Assay Description
Vasodilator activity assessed as ability to relax phenylephrine-induced contraction of Wistar rat aortic strips

J Med Chem 49: 2886-97 (2006)


Article DOI: 10.1021/jm0510530
BindingDB Entry DOI: 10.7270/Q2ZC82G7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%