BindingDB logo
myBDB logout

PubMed code 16759116

Compile data set for download or QSAR
Found 8 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50188722
PNG
(3-(3-trifluoromethyl)phenyl-8-methoxy-5H-indeno[1,...)
Show SMILES COc1ccc2C(=O)c3cc(nnc3-c2c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H11F3N2O2/c1-26-12-5-6-13-14(8-12)17-15(18(13)25)9-16(23-24-17)10-3-2-4-11(7-10)19(20,21)22/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.100n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in baboon liver mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50031058
PNG
(3-(3-trifluoromethyl)phenyl-7-methoxy-5H-indeno[1,...)
Show SMILES COc1ccc-2c(c1)C(=O)c1cc(nnc-21)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H11F3N2O2/c1-26-12-5-6-13-14(8-12)18(25)15-9-16(23-24-17(13)15)10-3-2-4-11(7-10)19(20,21)22/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 38n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in baboon liver mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50188723
PNG
(3-methyl-8-benzyloxy-5H-indeno[1,2-c]pyridazin-5-o...)
Show SMILES Cc1cc2C(=O)c3ccc(OCc4ccccc4)cc3-c2nn1
Show InChI InChI=1S/C19H14N2O2/c1-12-9-17-18(21-20-12)16-10-14(7-8-15(16)19(17)22)23-11-13-5-3-2-4-6-13/h2-10H,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in rat brain mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50188722
PNG
(3-(3-trifluoromethyl)phenyl-8-methoxy-5H-indeno[1,...)
Show SMILES COc1ccc2C(=O)c3cc(nnc3-c2c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H11F3N2O2/c1-26-12-5-6-13-14(8-12)17-15(18(13)25)9-16(23-24-17)10-3-2-4-11(7-10)19(20,21)22/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in human placental mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50188723
PNG
(3-methyl-8-benzyloxy-5H-indeno[1,2-c]pyridazin-5-o...)
Show SMILES Cc1cc2C(=O)c3ccc(OCc4ccccc4)cc3-c2nn1
Show InChI InChI=1S/C19H14N2O2/c1-12-9-17-18(21-20-12)16-10-14(7-8-15(16)19(17)22)23-11-13-5-3-2-4-6-13/h2-10H,11H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in rat brain mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50188724
PNG
(3-methyl-8-methoxy-5H-indeno[1,2-c]pyridazin-5-one...)
Show SMILES COc1ccc2C(=O)c3cc(C)nnc3-c2c1
Show InChI InChI=1S/C13H10N2O2/c1-7-5-11-12(15-14-7)10-6-8(17-2)3-4-9(10)13(11)16/h3-6H,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in rat brain mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50188724
PNG
(3-methyl-8-methoxy-5H-indeno[1,2-c]pyridazin-5-one...)
Show SMILES COc1ccc2C(=O)c3cc(C)nnc3-c2c1
Show InChI InChI=1S/C13H10N2O2/c1-7-5-11-12(15-14-7)10-6-8(17-2)3-4-9(10)13(11)16/h3-6H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-B in rat brain mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50031058
PNG
(3-(3-trifluoromethyl)phenyl-7-methoxy-5H-indeno[1,...)
Show SMILES COc1ccc-2c(c1)C(=O)c1cc(nnc-21)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H11F3N2O2/c1-26-12-5-6-13-14(8-12)18(25)15-9-16(23-24-17(13)15)10-3-2-4-11(7-10)19(20,21)22/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Facultés Universitaires N.D de la Paix

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in human placental mitochondria

J Med Chem 49: 3743-7 (2006)


Article DOI: 10.1021/jm051091j
BindingDB Entry DOI: 10.7270/Q2SF2VSN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%