Affinity Data by PubMed id=17010606

PubMed code 17010606

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50195804 (1-[1-(3,4-dimethylphenyl)cyclopropyl]-2-[2-(4-meth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 6213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.09.021 BindingDB Entry DOI: 10.7270/Q21V5DNX
Procter & Gamble Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50195802 (1-(2,3-dimethylphenyl)-2-[2-(4-methoxyphenyl)ethyl...) Show SMILES COc1ccc(CCn2nnn[n+]2-c2cccc(C)c2C)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 6213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.09.021 BindingDB Entry DOI: 10.7270/Q21V5DNX
Procter & Gamble Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50195800 (2-[2-(4-methoxyphenyl)ethyl]-1-[1-(4-methylphenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 6213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.09.021 BindingDB Entry DOI: 10.7270/Q21V5DNX
Procter & Gamble Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50195801 (2-[2-(4-methoxyphenyl)ethyl]-1-[1-(4-methylphenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 6213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.09.021 BindingDB Entry DOI: 10.7270/Q21V5DNX
Procter & Gamble Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50195805 (1-[1-(4-methylphenyl)cyclopropyl]-2-(3-phenylpropy...) Show SMILES Cc1ccc(cc1)C1(CC1)[n+]1nnnn1CCCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 6213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.09.021 BindingDB Entry DOI: 10.7270/Q21V5DNX
Procter & Gamble Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50195803 (1-(3,4-dichlorophenyl)-2-[2-(4-methoxyphenyl)ethyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Kv1.5 expressed in LTK- cells by whole cell patch clamp assay				Bioorg Med Chem Lett 16: 6213-8 (2006) Article DOI: 10.1016/j.bmcl.2006.09.021 BindingDB Entry DOI: 10.7270/Q21V5DNX
Procter & Gamble Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%