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PubMed code 17060518

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)
BDBM50197038
PNG
(6-(5-chloro-2,4-dimethoxyphenethyl)-6-cyclopentyl-...)
Show SMILES COc1cc(OC)c(CCC2(CC(=O)C(Sc3nc4nc(C)cc(C)n4n3)C(=O)O2)C2CCCC2)cc1Cl
Show InChI InChI=1S/C27H31ClN4O5S/c1-15-11-16(2)32-25(29-15)30-26(31-32)38-23-20(33)14-27(37-24(23)34,18-7-5-6-8-18)10-9-17-12-19(28)22(36-4)13-21(17)35-3/h11-13,18,23H,5-10,14H2,1-4H3
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of recombinant HCV 1b BK NS5B polymerase by primer/template-directed transcription assay


Antimicrob Agents Chemother 51: 95-102 (2006)


Article DOI: 10.1128/AAC.01008-06
BindingDB Entry DOI: 10.7270/Q25D8RGQ
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)
BDBM50024670
PNG
(AG-21033 | CHEMBL37541)
Show SMILES Cc1cc(SC2=C(O)OC(CCc3ccc(O)cc3)(CC2=O)C2CCCC2)c(cc1N)C(C)(C)C |c:5|
Show InChI InChI=1S/C29H37NO4S/c1-18-15-25(22(16-23(18)30)28(2,3)4)35-26-24(32)17-29(34-27(26)33,20-7-5-6-8-20)14-13-19-9-11-21(31)12-10-19/h9-12,15-16,20,31,33H,5-8,13-14,17,30H2,1-4H3
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 920n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of recombinant HCV 1b BK NS5B polymerase by primer/template-directed transcription assay


Antimicrob Agents Chemother 51: 95-102 (2006)


Article DOI: 10.1128/AAC.01008-06
BindingDB Entry DOI: 10.7270/Q25D8RGQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%