Affinity Data by PubMed id=17064065

PubMed code 17064065

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50145972 (2-Amino-4-[4-(5,7-dimethyl-2-propyl-imidazo[4,5-b]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
Università di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50197079 (1,2-dihydro-4-[4-[(5,7-dimethyl-2-ethyl-3H-imidazo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
Università di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50145979 (4-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyrid...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
Università di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50009714 (CHEMBL191 \| {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
Università di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50145981 (4-(4-((5,7-dimethyl-2-propyl-3H-imidazo[4,5-b]pyri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
Università di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50197082 (3-[4-[(5,7-dimethyl-2-propyl-3H-imidazo[4,5-b]pyri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contraction				J Med Chem 49: 6451-64 (2006) Article DOI: 10.1021/jm0603163 BindingDB Entry DOI: 10.7270/Q2WW7H9J
Università di Siena Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%