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PubMed code 17107799

Compile data set for download or QSAR
Found 31 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50476514
PNG
(CHEMBL232446)
Show SMILES Oc1nc(nc(C(=O)NCc2ccc(Cl)c(Cl)c2)c1O)-c1cccs1
Show InChI InChI=1S/C16H11Cl2N3O3S/c17-9-4-3-8(6-10(9)18)7-19-15(23)12-13(22)16(24)21-14(20-12)11-2-1-5-25-11/h1-6,22H,7H2,(H,19,23)(H,20,21,24)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50121880
PNG
(CHEMBL216874)
Show SMILES Oc1nc(nc(C(=O)NCc2ccc(F)cc2)c1O)-c1cccs1
Show InChI InChI=1S/C16H12FN3O3S/c17-10-5-3-9(4-6-10)8-18-15(22)12-13(21)16(23)20-14(19-12)11-2-1-7-24-11/h1-7,21H,8H2,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476515
PNG
(CHEMBL232226)
Show SMILES Oc1nc(nc(C(=O)Nc2cc3ccccc3s2)c1O)-c1cccs1
Show InChI InChI=1S/C17H11N3O3S2/c21-14-13(19-15(20-17(14)23)11-6-3-7-24-11)16(22)18-12-8-9-4-1-2-5-10(9)25-12/h1-8,21H,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476517
PNG
(CHEMBL226916)
Show SMILES Oc1nc(nc(C(=O)NCCc2ccccc2)c1O)-c1cccs1
Show InChI InChI=1S/C17H15N3O3S/c21-14-13(16(22)18-9-8-11-5-2-1-3-6-11)19-15(20-17(14)23)12-7-4-10-24-12/h1-7,10,21H,8-9H2,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476522
PNG
(CHEMBL390433)
Show SMILES Oc1nc(nc(C(=O)N[C@H]2CCc3ccccc23)c1O)-c1cccs1 |r|
Show InChI InChI=1S/C18H15N3O3S/c22-15-14(20-16(21-18(15)24)13-6-3-9-25-13)17(23)19-12-8-7-10-4-1-2-5-11(10)12/h1-6,9,12,22H,7-8H2,(H,19,23)(H,20,21,24)/t12-/m0/s1
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476536
PNG
(CHEMBL232228)
Show SMILES Oc1nc(nc(C(=O)NCc2c[nH]c3ccccc23)c1O)-c1cccs1
Show InChI InChI=1S/C18H14N4O3S/c23-15-14(21-16(22-18(15)25)13-6-3-7-26-13)17(24)20-9-10-8-19-12-5-2-1-4-11(10)12/h1-8,19,23H,9H2,(H,20,24)(H,21,22,25)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476511
PNG
(CHEMBL232444)
Show SMILES Oc1nc(nc(C(=O)NCc2ccc(Cl)cc2)c1O)-c1cccs1
Show InChI InChI=1S/C16H12ClN3O3S/c17-10-5-3-9(4-6-10)8-18-15(22)12-13(21)16(23)20-14(19-12)11-2-1-7-24-11/h1-7,21H,8H2,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476513
PNG
(CHEMBL234707)
Show SMILES Oc1nc(nc(C(=O)Nc2cccc3ccccc23)c1O)-c1cccs1
Show InChI InChI=1S/C19H13N3O3S/c23-16-15(21-17(22-19(16)25)14-9-4-10-26-14)18(24)20-13-8-3-6-11-5-1-2-7-12(11)13/h1-10,23H,(H,20,24)(H,21,22,25)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476526
PNG
(CHEMBL437361)
Show SMILES C[C@H](NC(=O)c1nc(nc(O)c1O)-c1cccs1)c1ccc2ccccc2c1 |r|
Show InChI InChI=1S/C21H17N3O3S/c1-12(14-9-8-13-5-2-3-6-15(13)11-14)22-20(26)17-18(25)21(27)24-19(23-17)16-7-4-10-28-16/h2-12,25H,1H3,(H,22,26)(H,23,24,27)/t12-/m0/s1
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476525
PNG
(CHEMBL232629)
Show SMILES Cc1cccc(CNC(=O)c2nc(nc(O)c2O)-c2cccs2)c1
Show InChI InChI=1S/C17H15N3O3S/c1-10-4-2-5-11(8-10)9-18-16(22)13-14(21)17(23)20-15(19-13)12-6-3-7-24-12/h2-8,21H,9H2,1H3,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476516
PNG
(CHEMBL232630)
Show SMILES Oc1nc(nc(C(=O)NCc2cccc(c2)-c2ccccc2)c1O)-c1cccs1
Show InChI InChI=1S/C22H17N3O3S/c26-19-18(24-20(25-22(19)28)17-10-5-11-29-17)21(27)23-13-14-6-4-9-16(12-14)15-7-2-1-3-8-15/h1-12,26H,13H2,(H,23,27)(H,24,25,28)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476512
PNG
(CHEMBL438113)
Show SMILES COc1cccc(CNC(=O)c2nc(nc(O)c2O)-c2cccs2)c1
Show InChI InChI=1S/C17H15N3O4S/c1-24-11-5-2-4-10(8-11)9-18-16(22)13-14(21)17(23)20-15(19-13)12-6-3-7-25-12/h2-8,21H,9H2,1H3,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476534
PNG
(CHEMBL232227)
Show SMILES Oc1nc(nc(C(=O)Nc2csc3ccccc23)c1O)-c1cccs1
Show InChI InChI=1S/C17H11N3O3S2/c21-14-13(19-15(20-17(14)23)12-6-3-7-24-12)16(22)18-10-8-25-11-5-2-1-4-9(10)11/h1-8,21H,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476518
PNG
(CHEMBL277754)
Show SMILES Cc1ccc(CNC(=O)c2nc(nc(O)c2O)-c2cccs2)cc1
Show InChI InChI=1S/C17H15N3O3S/c1-10-4-6-11(7-5-10)9-18-16(22)13-14(21)17(23)20-15(19-13)12-3-2-8-24-12/h2-8,21H,9H2,1H3,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476533
PNG
(CHEMBL398211)
Show SMILES Oc1nc(nc(C(=O)NCc2cccc(F)c2)c1O)-c1cccs1
Show InChI InChI=1S/C16H12FN3O3S/c17-10-4-1-3-9(7-10)8-18-15(22)12-13(21)16(23)20-14(19-12)11-5-2-6-24-11/h1-7,21H,8H2,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476539
PNG
(CHEMBL437708)
Show SMILES Oc1nc(nc(C(=O)NCc2ccccc2)c1O)-c1cccs1
Show InChI InChI=1S/C16H13N3O3S/c20-13-12(15(21)17-9-10-5-2-1-3-6-10)18-14(19-16(13)22)11-7-4-8-23-11/h1-8,20H,9H2,(H,17,21)(H,18,19,22)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476530
PNG
(CHEMBL232435)
Show SMILES COc1ccccc1CNC(=O)c1nc(nc(O)c1O)-c1cccs1
Show InChI InChI=1S/C17H15N3O4S/c1-24-11-6-3-2-5-10(11)9-18-16(22)13-14(21)17(23)20-15(19-13)12-7-4-8-25-12/h2-8,21H,9H2,1H3,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476528
PNG
(CHEMBL388419)
Show SMILES Oc1nc(nc(C(=O)Nc2cccs2)c1O)-c1cccs1
Show InChI InChI=1S/C13H9N3O3S2/c17-10-9(12(18)14-8-4-2-6-21-8)15-11(16-13(10)19)7-3-1-5-20-7/h1-6,17H,(H,14,18)(H,15,16,19)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476519
PNG
(CHEMBL232437)
Show SMILES Cc1ccccc1CNC(=O)c1nc(nc(O)c1O)-c1cccs1
Show InChI InChI=1S/C17H15N3O3S/c1-10-5-2-3-6-11(10)9-18-16(22)13-14(21)17(23)20-15(19-13)12-7-4-8-24-12/h2-8,21H,9H2,1H3,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476532
PNG
(CHEMBL389093)
Show SMILES Oc1nc(nc(C(=O)NCc2ccccc2-c2ccccc2)c1O)-c1cccs1
Show InChI InChI=1S/C22H17N3O3S/c26-19-18(24-20(25-22(19)28)17-11-6-12-29-17)21(27)23-13-15-9-4-5-10-16(15)14-7-2-1-3-8-14/h1-12,26H,13H2,(H,23,27)(H,24,25,28)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476510
PNG
(CHEMBL232445)
Show SMILES Oc1nc(nc(C(=O)NCc2ccccc2F)c1O)-c1cccs1
Show InChI InChI=1S/C16H12FN3O3S/c17-10-5-2-1-4-9(10)8-18-15(22)12-13(21)16(23)20-14(19-12)11-6-3-7-24-11/h1-7,21H,8H2,(H,18,22)(H,19,20,23)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476520
PNG
(CHEMBL232025)
Show SMILES Oc1nc(nc(C(=O)Nc2nccs2)c1O)-c1cccs1
Show InChI InChI=1S/C12H8N4O3S2/c17-8-7(10(18)16-12-13-3-5-21-12)14-9(15-11(8)19)6-2-1-4-20-6/h1-5,17H,(H,13,16,18)(H,14,15,19)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476529
PNG
(CHEMBL234922)
Show SMILES CN(C(=O)c1nc(nc(O)c1O)-c1cccs1)c1cccc2ccccc12
Show InChI InChI=1S/C20H15N3O3S/c1-23(14-9-4-7-12-6-2-3-8-13(12)14)20(26)16-17(24)19(25)22-18(21-16)15-10-5-11-27-15/h2-11,24H,1H3,(H,21,22,25)
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IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476538
PNG
(CHEMBL232436)
Show SMILES COc1ccc(CNC(=O)c2nc(nc(O)c2O)-c2cccs2)cc1
Show InChI InChI=1S/C17H15N3O4S/c1-24-11-6-4-10(5-7-11)9-18-16(22)13-14(21)17(23)20-15(19-13)12-3-2-8-25-12/h2-8,21H,9H2,1H3,(H,18,22)(H,19,20,23)
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n/an/a 550n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476535
PNG
(CHEMBL234923)
Show SMILES Oc1nc(nc(C(=O)N[C@@H]2CCc3ccccc23)c1O)-c1cccs1 |r|
Show InChI InChI=1S/C18H15N3O3S/c22-15-14(20-16(21-18(15)24)13-6-3-9-25-13)17(23)19-12-8-7-10-4-1-2-5-11(10)12/h1-6,9,12,22H,7-8H2,(H,19,23)(H,20,21,24)/t12-/m1/s1
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n/an/a 610n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476537
PNG
(CHEMBL234921)
Show SMILES C[C@@H](NC(=O)c1nc(nc(O)c1O)-c1cccs1)c1ccc2ccccc2c1 |r|
Show InChI InChI=1S/C21H17N3O3S/c1-12(14-9-8-13-5-2-3-6-15(13)11-14)22-20(26)17-18(25)21(27)24-19(23-17)16-7-4-10-28-16/h2-12,25H,1H3,(H,22,26)(H,23,24,27)/t12-/m1/s1
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n/an/a 610n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476527
PNG
(CHEMBL373760)
Show SMILES Oc1nc(nc(C(=O)Nc2ccccc2)c1O)-c1cccs1
Show InChI InChI=1S/C15H11N3O3S/c19-12-11(14(20)16-9-5-2-1-3-6-9)17-13(18-15(12)21)10-7-4-8-22-10/h1-8,19H,(H,16,20)(H,17,18,21)
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n/an/a 1.00E+3n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476524
PNG
(CHEMBL388420)
Show SMILES Oc1nc(nc(C(=O)Nc2cncs2)c1O)-c1cccs1
Show InChI InChI=1S/C12H8N4O3S2/c17-9-8(11(18)14-7-4-13-5-21-7)15-10(16-12(9)19)6-2-1-3-20-6/h1-5,17H,(H,14,18)(H,15,16,19)
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n/an/a 2.50E+3n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476531
PNG
(CHEMBL232024)
Show SMILES Oc1nc(nc(C(=O)NCc2ccncc2)c1O)-c1cccs1
Show InChI InChI=1S/C15H12N4O3S/c20-12-11(14(21)17-8-9-3-5-16-6-4-9)18-13(19-15(12)22)10-2-1-7-23-10/h1-7,20H,8H2,(H,17,21)(H,18,19,22)
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n/an/a 1.66E+4n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476523
PNG
(CHEMBL373761)
Show SMILES Oc1nc(nc(C(=O)NCC2CCCCC2)c1O)-c1cccs1
Show InChI InChI=1S/C16H19N3O3S/c20-13-12(15(21)17-9-10-5-2-1-3-6-10)18-14(19-16(13)22)11-7-4-8-23-11/h4,7-8,10,20H,1-3,5-6,9H2,(H,17,21)(H,18,19,22)
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n/an/a 5.00E+4n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
Integrase


(Human immunodeficiency virus 1)		BDBM50476521
PNG
(CHEMBL398210)
Show SMILES Oc1nc(nc(C(=O)NCc2ccc(cc2)-c2ccccc2)c1O)-c1cccs1
Show InChI InChI=1S/C22H17N3O3S/c26-19-18(24-20(25-22(19)28)17-7-4-12-29-17)21(27)23-13-14-8-10-16(11-9-14)15-5-2-1-3-6-15/h1-12,26H,13H2,(H,23,27)(H,24,25,28)
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n/an/a 5.00E+4n/an/an/an/an/an/a



IRBM-MRL Rome

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 17: 350-3 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.054
BindingDB Entry DOI: 10.7270/Q2FN18ZF
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%