Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50182801![]() ((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of GCase assessed as 4-methylumbelliferone release assay after 30 mins by fluorimetry | Nat Chem Biol 3: 101-7 (2007) Article DOI: 10.1038/nchembio850 BindingDB Entry DOI: 10.7270/Q2639PX9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |