Affinity Data by PubMed id=17325024

PubMed code 17325024

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of human URAT1-mediated urate uptake in HEK293 cells by competitive inhibition assay				Drug Metab Dispos 35: 981-6 (2007) Article DOI: 10.1124/dmd.106.012187 BindingDB Entry DOI: 10.7270/Q2KK9CPP
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of human URAT1-mediated urate uptake in HEK293 cells				Drug Metab Dispos 35: 981-6 (2007) Article DOI: 10.1124/dmd.106.012187 BindingDB Entry DOI: 10.7270/Q2KK9CPP
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of human URAT1-mediated urate uptake in HEK293 cells				Drug Metab Dispos 35: 981-6 (2007) Article DOI: 10.1124/dmd.106.012187 BindingDB Entry DOI: 10.7270/Q2KK9CPP
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Rattus norvegicus)	BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of human URAT1-mediated urate uptake in rat renal brush border membrane vesicles				Drug Metab Dispos 35: 981-6 (2007) Article DOI: 10.1124/dmd.106.012187 BindingDB Entry DOI: 10.7270/Q2KK9CPP
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of human URAT1-mediated urate uptake in HEK293 cells				Drug Metab Dispos 35: 981-6 (2007) Article DOI: 10.1124/dmd.106.012187 BindingDB Entry DOI: 10.7270/Q2KK9CPP
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM50026604 (1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)py...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Chinese University of Hong Kong Curated by ChEMBL					Assay Description Inhibition of human URAT1-mediated urate uptake in HEK293 cells				Drug Metab Dispos 35: 981-6 (2007) Article DOI: 10.1124/dmd.106.012187 BindingDB Entry DOI: 10.7270/Q2KK9CPP
The Chinese University of Hong Kong Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%