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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM36489 (BI-12H11) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 710 | 760 | n/a | n/a | n/a | 7.0 | n/a |
Burnham Institute for Medical Research | Assay Description In vitro kinase activity and selectivity was determined by using SelectScreen kinase profiling Z'-LYTE assay from Invitrogen. | ACS Chem Biol 2: 329-36 (2007) Article DOI: 10.1021/cb700025j BindingDB Entry DOI: 10.7270/Q2ZW1J99 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM36489 (BI-12H11) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.61E+3 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Burnham Institute for Medical Research | Assay Description The competitive binding between test compounds and a fluorescence p38 alpha inhibitor, SK&F 86002. | ACS Chem Biol 2: 329-36 (2007) Article DOI: 10.1021/cb700025j BindingDB Entry DOI: 10.7270/Q2ZW1J99 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
