Affinity Data by PubMed id=17562705

PubMed code 17562705

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50270042 ((2-hydroxy-4-morpholinophenyl)(phenyl)methanone \| ...) Show SMILES Oc1cc(ccc1C(=O)c1ccccc1)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of DNA-PK				J Biol Chem 282: 24463-70 (2007) Article DOI: 10.1074/jbc.M704741200 BindingDB Entry DOI: 10.7270/Q2VH5NMC
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50159620 (2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one ...) Show SMILES O=c1cc(nc2c3ccccc3ccn12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of DNA-PK				J Biol Chem 282: 24463-70 (2007) Article DOI: 10.1074/jbc.M704741200 BindingDB Entry DOI: 10.7270/Q2VH5NMC
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one \|...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of mTOR				J Biol Chem 282: 24463-70 (2007) Article DOI: 10.1074/jbc.M704741200 BindingDB Entry DOI: 10.7270/Q2VH5NMC
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50159620 (2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one ...) Show SMILES O=c1cc(nc2c3ccccc3ccn12)N1CCOCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of mTOR				J Biol Chem 282: 24463-70 (2007) Article DOI: 10.1074/jbc.M704741200 BindingDB Entry DOI: 10.7270/Q2VH5NMC
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50159620 (2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one ...) Show SMILES O=c1cc(nc2c3ccccc3ccn12)N1CCOCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of p110alpha/p85-alpha PI3K				J Biol Chem 282: 24463-70 (2007) Article DOI: 10.1074/jbc.M704741200 BindingDB Entry DOI: 10.7270/Q2VH5NMC
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50270042 ((2-hydroxy-4-morpholinophenyl)(phenyl)methanone \| ...) Show SMILES Oc1cc(ccc1C(=O)c1ccccc1)N1CCOCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of mTOR				J Biol Chem 282: 24463-70 (2007) Article DOI: 10.1074/jbc.M704741200 BindingDB Entry DOI: 10.7270/Q2VH5NMC
Stony Brook University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%