Affinity Data by PubMed id=17588744

PubMed code 17588744

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216518 (3-(2-(4-(pyridin-3-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216518 (3-(2-(4-(pyridin-3-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216517 (3-(2-biphenyl-4-ylmethyl-3-oxo-2,3-dihydro-1H-isoi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216519 (3-(2-(4-tert-butylbenzyl)-3-oxoisoindolin-5-yl)-N-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216517 (3-(2-biphenyl-4-ylmethyl-3-oxo-2,3-dihydro-1H-isoi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216515 (3-(2-benzyl-3-oxoisoindolin-5-yl)-N-hydroxyacrylam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216515 (3-(2-benzyl-3-oxoisoindolin-5-yl)-N-hydroxyacrylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216519 (3-(2-(4-tert-butylbenzyl)-3-oxoisoindolin-5-yl)-N-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216515 (3-(2-benzyl-3-oxoisoindolin-5-yl)-N-hydroxyacrylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216518 (3-(2-(4-(pyridin-3-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216517 (3-(2-biphenyl-4-ylmethyl-3-oxo-2,3-dihydro-1H-isoi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216519 (3-(2-(4-tert-butylbenzyl)-3-oxoisoindolin-5-yl)-N-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50216516 (3-(2-(4-(pyridin-4-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC4				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50216516 (3-(2-(4-(pyridin-4-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50216516 (3-(2-(4-(pyridin-4-yl)benzyl)-3-oxoisoindolin-5-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of human HDAC6				Bioorg Med Chem Lett 17: 4895-900 (2007) Article DOI: 10.1016/j.bmcl.2007.06.038 BindingDB Entry DOI: 10.7270/Q2SF2VW0
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%