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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University School of Medicine Curated by ChEMBL | Assay Description Inhibition of [3H]serotonin uptake in human wild type SERT transfected HEK293 cells | Science 317: 1390-3 (2007) Article DOI: 10.1126/science.1147614 BindingDB Entry DOI: 10.7270/Q2R49QG6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University School of Medicine Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine uptake in human wild type DAT transfected HEK293 cells | Science 317: 1390-3 (2007) Article DOI: 10.1126/science.1147614 BindingDB Entry DOI: 10.7270/Q2R49QG6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
