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PubMed code 17804230

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 10 subunit alpha


(Homo sapiens (Human))		BDBM50220948
PNG
(CID44435592 | Sch 725737 (1))
Show SMILES CC(C)CCC[C@@](C)(O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O[C@@H]4O[C@H](C)[C@@H](O)[C@H](O[C@@H]5OC[C@@H](O[C@@H]6O[C@H](C)[C@@H](O[C@@H]7OC[C@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]6O[C@H](C)[C@H](O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O[C@@H]5O[C@H](C)[C@@H](O)[C@H](O)[C@H]5O)[C@H]4O)[C@H]4C[C@H](CC[C@]4(C)C3=CC[C@]12C)OS([O-])(=O)=O |c:90|
Show InChI InChI=1S/C61H102O30S/c1-23(2)11-10-16-61(9,75)36-13-12-30-29-20-34(32-19-28(91-92(76,77)78)14-17-59(32,7)31(29)15-18-60(30,36)8)85-56-48(74)50(39(65)26(5)83-56)88-57-51(89-54-45(71)42(68)37(63)24(3)81-54)41(67)35(22-80-57)86-58-52(90-55-46(72)43(69)38(64)25(4)82-55)47(73)49(27(6)84-58)87-53-44(70)40(66)33(62)21-79-53/h15,23-30,32-58,62-75H,10-14,16-22H2,1-9H3,(H,76,77,78)/p-1/t24-,25-,26-,27-,28+,29+,30+,32-,33+,34+,35-,36+,37-,38+,39-,40+,41+,42+,43+,44-,45-,46-,47+,48-,49-,50+,51-,52-,53+,54+,55+,56+,57+,58+,59-,60+,61-/m1/s1
PDB

UniProtKB/SwissProt

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of sodium channel NaV1.8 expressed in rat ND7/23 cells by FLIPR assay

Bioorg Med Chem Lett 17: 5543-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.08.025
BindingDB Entry DOI: 10.7270/Q26T0NGW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%