Found 9 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373067
(CHEMBL1162089)Show SMILES C[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)[C@H](NC(=O)[C@H](CCCCNC(=O)c1ccccc1N)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)C(N)=O |r| Show InChI InChI=1S/C47H78N6O33P2/c1-16(79-46-38(34(63)28(57)22(12-54)81-46)85-44-36(65)32(61)30(59)24(83-44)14-77-87(71,72)73)26(40(49)67)53-42(69)21(10-6-7-11-50-41(68)19-8-4-5-9-20(19)48)52-43(70)27(51-18(3)56)17(2)80-47-39(35(64)29(58)23(13-55)82-47)86-45-37(66)33(62)31(60)25(84-45)15-78-88(74,75)76/h4-5,8-9,16-17,21-39,44-47,54-55,57-66H,6-7,10-15,48H2,1-3H3,(H2,49,67)(H,50,68)(H,51,56)(H,52,70)(H,53,69)(H2,71,72,73)(H2,74,75,76)/t16-,17-,21+,22-,23-,24-,25-,26+,27+,28-,29-,30-,31-,32+,33+,34+,35+,36+,37+,38+,39+,44-,45-,46+,47+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373069
(CHEMBL1162088)Show SMILES C[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)C(N)=O |r| Show InChI InChI=1S/C42H75N5O33P2/c1-13(73-41-34(30(58)24(52)18(9-48)75-41)79-39-32(60)28(56)26(54)20(77-39)11-71-81(65,66)67)22(36(43)62)47-37(63)17(7-5-6-8-44-15(3)50)46-38(64)23(45-16(4)51)14(2)74-42-35(31(59)25(53)19(10-49)76-42)80-40-33(61)29(57)27(55)21(78-40)12-72-82(68,69)70/h13-14,17-35,39-42,48-49,52-61H,5-12H2,1-4H3,(H2,43,62)(H,44,50)(H,45,51)(H,46,64)(H,47,63)(H2,65,66,67)(H2,68,69,70)/t13-,14-,17+,18-,19-,20-,21-,22+,23+,24-,25-,26-,27-,28+,29+,30+,31+,32+,33+,34+,35+,39-,40-,41+,42+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373063
(CHEMBL260987)Show SMILES O[C@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OCCCCCCCCCCCCO[C@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]2O)[C@H]1O |r| Show InChI InChI=1S/C24H48O18P2/c25-17-15(13-39-43(31,32)33)41-23(21(29)19(17)27)37-11-9-7-5-3-1-2-4-6-8-10-12-38-24-22(30)20(28)18(26)16(42-24)14-40-44(34,35)36/h15-30H,1-14H2,(H2,31,32,33)(H2,34,35,36)/t15-,16-,17-,18-,19+,20+,21+,22+,23+,24+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373064
(CHEMBL448108)Show SMILES O[C@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OCCCCCCCCCCO[C@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]2O)[C@H]1O |r| Show InChI InChI=1S/C22H44O18P2/c23-15-13(11-37-41(29,30)31)39-21(19(27)17(15)25)35-9-7-5-3-1-2-4-6-8-10-36-22-20(28)18(26)16(24)14(40-22)12-38-42(32,33)34/h13-28H,1-12H2,(H2,29,30,31)(H2,32,33,34)/t13-,14-,15-,16-,17+,18+,19+,20+,21+,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373065
(CHEMBL406598)Show SMILES O[C@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OCCCCCCO[C@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]2O)[C@H]1O |r| Show InChI InChI=1S/C18H36O18P2/c19-11-9(7-33-37(25,26)27)35-17(15(23)13(11)21)31-5-3-1-2-4-6-32-18-16(24)14(22)12(20)10(36-18)8-34-38(28,29)30/h9-24H,1-8H2,(H2,25,26,27)(H2,28,29,30)/t9-,10-,11-,12-,13+,14+,15+,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373070
(CHEMBL261860)Show SMILES O[C@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H](OCCCCCCCCO[C@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]2O)[C@H]1O |r| Show InChI InChI=1S/C20H40O18P2/c21-13-11(9-35-39(27,28)29)37-19(17(25)15(13)23)33-7-5-3-1-2-4-6-8-34-20-18(26)16(24)14(22)12(38-20)10-36-40(30,31)32/h11-26H,1-10H2,(H2,27,28,29)(H2,30,31,32)/t11-,12-,13-,14-,15+,16+,17+,18+,19+,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373066
(CHEMBL257975)Show SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50275807
(mannose 6-phosphate)Show SMILES O[C@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/p-1/t2-,3-,4+,5+,6+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50373068
(CHEMBL1162087)Show SMILES C[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O)C(N)=O |r| Show InChI InChI=1S/C40H73N5O32P2/c1-12(70-39-32(28(55)22(49)16(8-46)72-39)76-37-30(57)26(53)24(51)18(74-37)10-68-78(62,63)64)20(34(42)59)45-35(60)15(6-4-5-7-41)44-36(61)21(43-14(3)48)13(2)71-40-33(29(56)23(50)17(9-47)73-40)77-38-31(58)27(54)25(52)19(75-38)11-69-79(65,66)67/h12-13,15-33,37-40,46-47,49-58H,4-11,41H2,1-3H3,(H2,42,59)(H,43,48)(H,44,61)(H,45,60)(H2,62,63,64)(H2,65,66,67)/t12-,13-,15+,16-,17-,18-,19-,20+,21+,22-,23-,24-,25-,26+,27+,28+,29+,30+,31+,32+,33+,37-,38-,39+,40+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description
Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094
BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this
Ligand-Target Pair | |
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