Affinity Data by PubMed id=18226898

PubMed code 18226898

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50233180 (1-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)ur...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50233178 (1-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)ure...) Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50233182 (1-(4-(methylsulfonyl)phenyl)-3-phenylurea \| CHEMBL...) Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50233179 (1-(4-chlorophenyl)-3-(4-(methylsulfonyl)phenyl)ure...) Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50233181 (1-(4-(methylsulfonyl)phenyl)-3-p-tolylurea \| CHEMB...) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50233182 (1-(4-(methylsulfonyl)phenyl)-3-phenylurea \| CHEMBL...) Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50233181 (1-(4-(methylsulfonyl)phenyl)-3-p-tolylurea \| CHEMB...) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50233179 (1-(4-chlorophenyl)-3-(4-(methylsulfonyl)phenyl)ure...) Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50233178 (1-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)ure...) Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50233180 (1-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)ur...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by chemiluminescent assay				Bioorg Med Chem Lett 18: 1336-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.021 BindingDB Entry DOI: 10.7270/Q2Z89C4T
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%