Affinity Data by PubMed id=18321713

PubMed code 18321713

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50220067 (11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50376170 (CHEMBL265446) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50236805 (4,5-dihydro-11H-2,5,11-triaza-benzo[a]trindene-1,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50216165 (1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50216157 (11H-2,5,11,11b-Tetraaza-benzo[a]trindene-4,6-dione...) Show SMILES O=C1NC(=O)c2c1c1cncn1c1[nH]c3ccccc3c21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50220074 (CHEMBL243930 \| benzo[a]pyrrolo[3,4-c]carbazole-1,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50220068 (4,7-dihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3(2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	311	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50376169 (CHEMBL259432) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50376171 (CHEMBL265691) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
Universit£ Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%