Affinity Data by PubMed id=18343125

PubMed code 18343125

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50162160 (1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of Her2 expressed in CSH12 cells by western blot analysis				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50376366 (CHEMBL259395) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of EGFR expressed in DHER14 cells by western blot analysis				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50376365 (CHEMBL259394) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of EGFR expressed in DHER14 cells by western blot analysis				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50162160 (1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of EGFR expressed in DHER14 cells by western blot analysis				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50376365 (CHEMBL259394) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of Her2 expressed in CSH12 cells by western blot analysis				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50376366 (CHEMBL259395) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of Her2 expressed in CSH12 cells by western blot analysis				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50376366 (CHEMBL259395) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of IGF1R by ELISA				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50162160 (1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of IGF1R by ELISA				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50376365 (CHEMBL259394) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Hospital Curated by ChEMBL					Assay Description Inhibition of IGF1R by ELISA				Bioorg Med Chem 16: 4242-51 (2008) Article DOI: 10.1016/j.bmc.2008.02.081 BindingDB Entry DOI: 10.7270/Q2B85903
Hadassah Hebrew University Hospital Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%