Found 3 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50375265
(CYCLOPROPYLCYFUSINE)Show InChI InChI=1S/C11H12N2O/c14-9-3-1-2-8-11-4-10(11,5-12-6-11)7-13(8)9/h1-3,12H,4-7H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR in GH4C1 cells |
Bioorg Med Chem Lett 18: 2316-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.078
BindingDB Entry DOI: 10.7270/Q22808GK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50375266
((+/-)-CYFUSINE | CYFUSINE)Show InChI InChI=1S/C10H12N2O/c13-10-3-1-2-9-8-5-11-4-7(8)6-12(9)10/h1-3,7-8,11H,4-6H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR in GH4C1 cells |
Bioorg Med Chem Lett 18: 2316-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.078
BindingDB Entry DOI: 10.7270/Q22808GK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50143282
((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)Show InChI InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 5.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR in GH4C1 cells |
Bioorg Med Chem Lett 18: 2316-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.078
BindingDB Entry DOI: 10.7270/Q22808GK |
More data for this
Ligand-Target Pair | |
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