Affinity Data by PubMed id=18391212

PubMed code 18391212

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM30328 (MFA-3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.0	4
Merck Research Laboratories					Assay Description To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...				Proc Natl Acad Sci U S A 105: 5337-42 (2008) Article DOI: 10.1073/pnas.0710981105 BindingDB Entry DOI: 10.7270/Q2QC01VJ
Merck Research Laboratories					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM30327 (MFA-2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	509	n/a	n/a	7.0	4
Merck Research Laboratories					Assay Description To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...				Proc Natl Acad Sci U S A 105: 5337-42 (2008) Article DOI: 10.1073/pnas.0710981105 BindingDB Entry DOI: 10.7270/Q2QC01VJ
Merck Research Laboratories					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM30326 (MFA-1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	16.9	n/a	n/a	7.0	4
Merck Research Laboratories					Assay Description To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...				Proc Natl Acad Sci U S A 105: 5337-42 (2008) Article DOI: 10.1073/pnas.0710981105 BindingDB Entry DOI: 10.7270/Q2QC01VJ
Merck Research Laboratories					More data for this Ligand-Target Pair				3D Structure (crystal)
Bile acid receptor (Homo sapiens (Human))	BDBM21674 ((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	8.30E+3	n/a	n/a	7.0	4
Merck Research Laboratories					Assay Description To each well of a 96-well assay plate, assay buffer was added containing purified GST-FXR, Eu-labeled anti-GST antibody (Perkin-Elmer), streptavidin-...				Proc Natl Acad Sci U S A 105: 5337-42 (2008) Article DOI: 10.1073/pnas.0710981105 BindingDB Entry DOI: 10.7270/Q2QC01VJ
Merck Research Laboratories					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%