Found 23 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50007674
((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)Show SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1 | PDB
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| PDB
Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377833
(CHEMBL413998)Show InChI InChI=1S/C21H26N2O/c1-16(21(24)19-7-9-20(22)10-8-19)23-13-11-18(12-14-23)15-17-5-3-2-4-6-17/h2-10,16,18H,11-15,22H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377825
(CHEMBL258032)Show SMILES OC(CN1CCC(Cc2ccccc2)CC1)c1ccc(O)cc1 |w:1.0| Show InChI InChI=1S/C20H25NO2/c22-19-8-6-18(7-9-19)20(23)15-21-12-10-17(11-13-21)14-16-4-2-1-3-5-16/h1-9,17,20,22-23H,10-15H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377831
(CHEMBL255697)Show SMILES CC(C(O)c1ccc(N)cc1)N1CCC(Cc2ccccc2)CC1 |w:2.2,1.0| Show InChI InChI=1S/C21H28N2O/c1-16(21(24)19-7-9-20(22)10-8-19)23-13-11-18(12-14-23)15-17-5-3-2-4-6-17/h2-10,16,18,21,24H,11-15,22H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377831
(CHEMBL255697)Show SMILES CC(C(O)c1ccc(N)cc1)N1CCC(Cc2ccccc2)CC1 |w:2.2,1.0| Show InChI InChI=1S/C21H28N2O/c1-16(21(24)19-7-9-20(22)10-8-19)23-13-11-18(12-14-23)15-17-5-3-2-4-6-17/h2-10,16,18,21,24H,11-15,22H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377834
(CHEMBL401882)Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C23H28N2O2/c1-17(23(27)21-8-10-22(11-9-21)24-18(2)26)25-14-12-20(13-15-25)16-19-6-4-3-5-7-19/h3-11,17,20H,12-16H2,1-2H3,(H,24,26) | PDB
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377828
(CHEMBL257783)Show InChI InChI=1S/C20H23NO2/c22-19-8-6-18(7-9-19)20(23)15-21-12-10-17(11-13-21)14-16-4-2-1-3-5-16/h1-9,17,22H,10-15H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 141 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377827
(CHEMBL257989)Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)[N+]([O-])=O)CC1 Show InChI InChI=1S/C20H22N2O4/c23-19-7-3-17(4-8-19)20(24)14-21-11-9-16(10-12-21)13-15-1-5-18(6-2-15)22(25)26/h1-8,16,23H,9-14H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377826
(CHEMBL402979)Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377829
(CHEMBL255895)Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)C(=C)CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H24N2O3/c1-17(22(25)20-7-9-21(10-8-20)24(26)27)16-23-13-11-19(12-14-23)15-18-5-3-2-4-6-18/h2-10,19H,1,11-16H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 248 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377832
(CHEMBL401688)Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 493 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377830
(CHEMBL401806)Show InChI InChI=1S/C23H27NO2/c1-18(23(25)21-8-10-22(26-2)11-9-21)17-24-14-12-20(13-15-24)16-19-6-4-3-5-7-19/h3-11,20H,1,12-17H2,2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 527 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat)) | BDBM50377835
(CHEMBL256083)Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(cc1)N=C=S Show InChI InChI=1S/C22H24N2OS/c1-17(22(25)20-7-9-21(10-8-20)23-16-26)24-13-11-19(12-14-24)15-18-5-3-2-4-6-18/h2-10,17,19H,11-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 679 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Displacement of [3H]ifenprodil from rat brain membrane NR2B receptor |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human)) | BDBM50007674
((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)Show SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human)) | BDBM50377832
(CHEMBL401688)Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human)) | BDBM50377826
(CHEMBL402979)Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2A
(Homo sapiens (Human)) | BDBM50377826
(CHEMBL402979)Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human)) | BDBM50377830
(CHEMBL401806)Show InChI InChI=1S/C23H27NO2/c1-18(23(25)21-8-10-22(26-2)11-9-21)17-24-14-12-20(13-15-24)16-19-6-4-3-5-7-19/h3-11,20H,1,12-17H2,2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human)) | BDBM50377832
(CHEMBL401688)Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren... |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2B
(Homo sapiens (Human)) | BDBM50377826
(CHEMBL402979)Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren... |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2A
(Homo sapiens (Human)) | BDBM50377826
(CHEMBL402979)Show SMILES Oc1ccc(cc1)C(=O)CN1CCC(Cc2ccc(cc2)N=C=S)CC1 Show InChI InChI=1S/C21H22N2O2S/c24-20-7-3-18(4-8-20)21(25)14-23-11-9-17(10-12-23)13-16-1-5-19(6-2-16)22-15-26/h1-8,17,24H,9-14H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2A
(Homo sapiens (Human)) | BDBM50377832
(CHEMBL401688)Show SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C23H27ClN2O2/c1-17(23(28)20-7-9-21(10-8-20)25-22(27)16-24)26-13-11-19(12-14-26)15-18-5-3-2-4-6-18/h2-10,17,19H,11-16H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1/2A
(Homo sapiens (Human)) | BDBM50377830
(CHEMBL401806)Show InChI InChI=1S/C23H27NO2/c1-18(23(25)21-8-10-22(26-2)11-9-21)17-24-14-12-20(13-15-24)16-19-6-4-3-5-7-19/h3-11,20H,1,12-17H2,2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Universit£ Louis Pasteur de Strasbourg
Curated by ChEMBL
| Assay Description
Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response |
Bioorg Med Chem Lett 18: 2765-70 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.019
BindingDB Entry DOI: 10.7270/Q21C1XR4 |
More data for this
Ligand-Target Pair | |
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