Found 102 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373386
(CHEMBL255663)Show InChI InChI=1S/C15H20N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h3-5,8,11,13H,1-2,6-7,9-10,16H2/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373385
(CHEMBL255450)Show InChI InChI=1S/C15H18N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h1,4-5,8,11,13H,2,6-7,9-10,16H2/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373399
(CHEMBL401677)Show SMILES CCN(C=C)C(=O)[C@]1(C[C@H]1CN)c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H22N2O3/c1-3-19(4-2)16(20)17(10-13(17)11-18)12-5-6-14-15(9-12)22-8-7-21-14/h3,5-6,9,13H,1,4,7-8,10-11,18H2,2H3/t13-,17+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373405
(CHEMBL257389)Show InChI InChI=1S/C15H21FN2O2S/c1-11(16)9-18(4-5-20-2)14(19)15(7-13(15)8-17)12-3-6-21-10-12/h3,6,10,13H,1,4-5,7-9,17H2,2H3/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50239791
((1S,2R)-N-allyl-2-(aminomethyl)-N-ethyl-1-(thiophe...)Show InChI InChI=1S/C14H20N2OS/c1-3-6-16(4-2)13(17)14(8-12(14)9-15)11-5-7-18-10-11/h3,5,7,10,12H,1,4,6,8-9,15H2,2H3/t12-,14+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373407
(CHEMBL257388)Show InChI InChI=1S/C15H16N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h1-2,5,8,11,13H,6-7,9-10,16H2/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373403
(CHEMBL404027)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCc2ccccc2C1)c1ccsc1 Show InChI InChI=1S/C18H20N2OS/c19-10-16-9-18(16,15-6-8-22-12-15)17(21)20-7-5-13-3-1-2-4-14(13)11-20/h1-4,6,8,12,16H,5,7,9-11,19H2/t16-,18+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373411
(CHEMBL255449)Show InChI InChI=1S/C15H20N2OS/c1-2-6-17(13-3-4-13)14(18)15(8-12(15)9-16)11-5-7-19-10-11/h2,5,7,10,12-13H,1,3-4,6,8-9,16H2/t12-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373400
(CHEMBL402089)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1C=COc2ccccc12)c1ccsc1 |c:9| Show InChI InChI=1S/C17H16N2O2S/c18-10-13-9-17(13,12-5-8-22-11-12)16(20)19-6-7-21-15-4-2-1-3-14(15)19/h1-8,11,13H,9-10,18H2/t13-,17+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373412
(CHEMBL403616)Show InChI InChI=1S/C15H22N2O2S/c1-3-5-17(6-7-19-2)14(18)15(9-13(15)10-16)12-4-8-20-11-12/h3-4,8,11,13H,1,5-7,9-10,16H2,2H3/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373401
(CHEMBL255246)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCCc2ccccc12)c1ccsc1 Show InChI InChI=1S/C18H20N2OS/c19-11-15-10-18(15,14-7-9-22-12-14)17(21)20-8-3-5-13-4-1-2-6-16(13)20/h1-2,4,6-7,9,12,15H,3,5,8,10-11,19H2/t15-,18+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373411
(CHEMBL255449)Show InChI InChI=1S/C15H20N2OS/c1-2-6-17(13-3-4-13)14(18)15(8-12(15)9-16)11-5-7-19-10-11/h2,5,7,10,12-13H,1,3-4,6,8-9,16H2/t12-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373397
(CHEMBL257809)Show InChI InChI=1S/C13H19BrN2OS/c1-3-16(4-2)12(17)13(7-9(13)8-15)10-5-6-11(14)18-10/h5-6,9H,3-4,7-8,15H2,1-2H3/t9-,13-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373408
(CHEMBL439423)Show InChI InChI=1S/C13H16N2OS/c1-3-5-15(2)12(16)13(7-11(13)8-14)10-4-6-17-9-10/h1,4,6,9,11H,5,7-8,14H2,2H3/t11-,13+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373402
(CHEMBL257348)Show SMILES NC[C@@H]1C[C@@]1(C(=O)C1NCc2ccccc12)c1ccsc1 |w:7.7| Show InChI InChI=1S/C17H18N2OS/c18-8-13-7-17(13,12-5-6-21-10-12)16(20)15-14-4-2-1-3-11(14)9-19-15/h1-6,10,13,15,19H,7-9,18H2/t13-,15?,17+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50032379
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373396
(CHEMBL257810)Show InChI InChI=1S/C13H19ClN2OS/c1-3-16(4-2)12(17)13(7-9(13)8-15)10-5-6-11(14)18-10/h5-6,9H,3-4,7-8,15H2,1-2H3/t9-,13-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373405
(CHEMBL257389)Show InChI InChI=1S/C15H21FN2O2S/c1-11(16)9-18(4-5-20-2)14(19)15(7-13(15)8-17)12-3-6-21-10-12/h3,6,10,13H,1,4-5,7-9,17H2,2H3/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373406
(CHEMBL402027)Show InChI InChI=1S/C13H17FN2OS/c1-9(14)7-16(2)12(17)13(5-11(13)6-15)10-3-4-18-8-10/h3-4,8,11H,1,5-7,15H2,2H3/t11-,13+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373409
(CHEMBL257390)Show InChI InChI=1S/C15H20N2O2S/c1-3-5-17(6-7-19-2)14(18)15(9-13(15)10-16)12-4-8-20-11-12/h1,4,8,11,13H,5-7,9-10,16H2,2H3/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373412
(CHEMBL403616)Show InChI InChI=1S/C15H22N2O2S/c1-3-5-17(6-7-19-2)14(18)15(9-13(15)10-16)12-4-8-20-11-12/h3-4,8,11,13H,1,5-7,9-10,16H2,2H3/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373398
(CHEMBL401676)Show InChI InChI=1S/C13H20N2OS/c1-3-15(4-2)12(16)13(7-11(13)8-14)10-5-6-17-9-10/h5-6,9,11H,3-4,7-8,14H2,1-2H3/t11-,13+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373406
(CHEMBL402027)Show InChI InChI=1S/C13H17FN2OS/c1-9(14)7-16(2)12(17)13(5-11(13)6-15)10-3-4-18-8-10/h3-4,8,11H,1,5-7,15H2,2H3/t11-,13+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373413
(CHEMBL257603)Show InChI InChI=1S/C13H18N2OS/c1-3-5-15(2)12(16)13(7-11(13)8-14)10-4-6-17-9-10/h3-4,6,9,11H,1,5,7-8,14H2,2H3/t11-,13+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373409
(CHEMBL257390)Show InChI InChI=1S/C15H20N2O2S/c1-3-5-17(6-7-19-2)14(18)15(9-13(15)10-16)12-4-8-20-11-12/h1,4,8,11,13H,5-7,9-10,16H2,2H3/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373399
(CHEMBL401677)Show SMILES CCN(C=C)C(=O)[C@]1(C[C@H]1CN)c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H22N2O3/c1-3-19(4-2)16(20)17(10-13(17)11-18)12-5-6-14-15(9-12)22-8-7-21-14/h3,5-6,9,13H,1,4,7-8,10-11,18H2,2H3/t13-,17+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373393
(CHEMBL257338)Show InChI InChI=1S/C17H22N2OS/c1-3-19(4-2)16(20)17(10-13(17)11-18)15-9-12-7-5-6-8-14(12)21-15/h5-9,13H,3-4,10-11,18H2,1-2H3/t13-,17-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373385
(CHEMBL255450)Show InChI InChI=1S/C15H18N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h1,4-5,8,11,13H,2,6-7,9-10,16H2/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373402
(CHEMBL257348)Show SMILES NC[C@@H]1C[C@@]1(C(=O)C1NCc2ccccc12)c1ccsc1 |w:7.7| Show InChI InChI=1S/C17H18N2OS/c18-8-13-7-17(13,12-5-6-21-10-12)16(20)15-14-4-2-1-3-11(14)9-19-15/h1-6,10,13,15,19H,7-9,18H2/t13-,15?,17+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50239784
((1R,2R)-2-(aminomethyl)-N,N-diethyl-1-(thiophen-2-...)Show InChI InChI=1S/C13H20N2OS/c1-3-15(4-2)12(16)13(8-10(13)9-14)11-6-5-7-17-11/h5-7,10H,3-4,8-9,14H2,1-2H3/t10-,13-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373386
(CHEMBL255663)Show InChI InChI=1S/C15H20N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h3-5,8,11,13H,1-2,6-7,9-10,16H2/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373407
(CHEMBL257388)Show InChI InChI=1S/C15H16N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h1-2,5,8,11,13H,6-7,9-10,16H2/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373413
(CHEMBL257603)Show InChI InChI=1S/C13H18N2OS/c1-3-5-15(2)12(16)13(7-11(13)8-14)10-4-6-17-9-10/h3-4,6,9,11H,1,5,7-8,14H2,2H3/t11-,13+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373408
(CHEMBL439423)Show InChI InChI=1S/C13H16N2OS/c1-3-5-15(2)12(16)13(7-11(13)8-14)10-4-6-17-9-10/h1,4,6,9,11H,5,7-8,14H2,2H3/t11-,13+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50239791
((1S,2R)-N-allyl-2-(aminomethyl)-N-ethyl-1-(thiophe...)Show InChI InChI=1S/C14H20N2OS/c1-3-6-16(4-2)13(17)14(8-12(14)9-15)11-5-7-18-10-11/h3,5,7,10,12H,1,4,6,8-9,15H2,2H3/t12-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373389
(CHEMBL257130)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1cc2cc(F)ccc2s1 Show InChI InChI=1S/C17H21FN2OS/c1-3-20(4-2)16(21)17(9-12(17)10-19)15-8-11-7-13(18)5-6-14(11)22-15/h5-8,12H,3-4,9-10,19H2,1-2H3/t12-,17-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373387
(CHEMBL257808)Show InChI InChI=1S/C17H22N2OS/c1-3-19(4-2)16(20)17(9-12(17)10-18)14-11-21-15-8-6-5-7-13(14)15/h5-8,11-12H,3-4,9-10,18H2,1-2H3/t12-,17-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373404
(CHEMBL402090)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCCC=C1)c1ccsc1 |c:12| Show InChI InChI=1S/C14H18N2OS/c15-9-12-8-14(12,11-4-7-18-10-11)13(17)16-5-2-1-3-6-16/h2,4-5,7,10,12H,1,3,6,8-9,15H2/t12-,14+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373394
(CHEMBL258013)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1sc(Cl)c(Cl)c1Cl Show InChI InChI=1S/C13H17Cl3N2OS/c1-3-18(4-2)12(19)13(5-7(13)6-17)10-8(14)9(15)11(16)20-10/h7H,3-6,17H2,1-2H3/t7-,13-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373389
(CHEMBL257130)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1cc2cc(F)ccc2s1 Show InChI InChI=1S/C17H21FN2OS/c1-3-20(4-2)16(21)17(9-12(17)10-19)15-8-11-7-13(18)5-6-14(11)22-15/h5-8,12H,3-4,9-10,19H2,1-2H3/t12-,17-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50032379
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373403
(CHEMBL404027)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCc2ccccc2C1)c1ccsc1 Show InChI InChI=1S/C18H20N2OS/c19-10-16-9-18(16,15-6-8-22-12-15)17(21)20-7-5-13-3-1-2-4-14(13)11-20/h1-4,6,8,12,16H,5,7,9-11,19H2/t16-,18+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373400
(CHEMBL402089)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1C=COc2ccccc12)c1ccsc1 |c:9| Show InChI InChI=1S/C17H16N2O2S/c18-10-13-9-17(13,12-5-8-22-11-12)16(20)19-6-7-21-15-4-2-1-3-14(15)19/h1-8,11,13H,9-10,18H2/t13-,17+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373397
(CHEMBL257809)Show InChI InChI=1S/C13H19BrN2OS/c1-3-16(4-2)12(17)13(7-9(13)8-15)10-5-6-11(14)18-10/h5-6,9H,3-4,7-8,15H2,1-2H3/t9-,13-/m0/s1 | PDB
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UniChem
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PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373401
(CHEMBL255246)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCCc2ccccc12)c1ccsc1 Show InChI InChI=1S/C18H20N2OS/c19-11-15-10-18(15,14-7-9-22-12-14)17(21)20-8-3-5-13-4-1-2-6-16(13)20/h1-2,4,6-7,9,12,15H,3,5,8,10-11,19H2/t15-,18+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50239784
((1R,2R)-2-(aminomethyl)-N,N-diethyl-1-(thiophen-2-...)Show InChI InChI=1S/C13H20N2OS/c1-3-15(4-2)12(16)13(8-10(13)9-14)11-6-5-7-17-11/h5-7,10H,3-4,8-9,14H2,1-2H3/t10-,13-/m0/s1 | PDB
KEGG
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DrugBank
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373396
(CHEMBL257810)Show InChI InChI=1S/C13H19ClN2OS/c1-3-16(4-2)12(17)13(7-9(13)8-15)10-5-6-11(14)18-10/h5-6,9H,3-4,7-8,15H2,1-2H3/t9-,13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373395
(CHEMBL401804)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C13H18Cl2N2OS/c1-3-17(4-2)12(18)13(6-8(13)7-16)10-5-9(14)11(15)19-10/h5,8H,3-4,6-7,16H2,1-2H3/t8-,13-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373410
(CHEMBL255448)Show InChI InChI=1S/C13H20N2O2S/c1-15(4-5-17-2)12(16)13(7-11(13)8-14)10-3-6-18-9-10/h3,6,9,11H,4-5,7-8,14H2,1-2H3/t11-,13+/m0/s1 | PDB
KEGG
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DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373393
(CHEMBL257338)Show InChI InChI=1S/C17H22N2OS/c1-3-19(4-2)16(20)17(10-13(17)11-18)15-9-12-7-5-6-8-14(12)21-15/h5-9,13H,3-4,10-11,18H2,1-2H3/t13-,17-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373398
(CHEMBL401676)Show InChI InChI=1S/C13H20N2OS/c1-3-15(4-2)12(16)13(7-11(13)8-14)10-5-6-17-9-10/h5-6,9,11H,3-4,7-8,14H2,1-2H3/t11-,13+/m0/s1 | PDB
KEGG
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DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373410
(CHEMBL255448)Show InChI InChI=1S/C13H20N2O2S/c1-15(4-5-17-2)12(16)13(7-11(13)8-14)10-3-6-18-9-10/h3,6,9,11H,4-5,7-8,14H2,1-2H3/t11-,13+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373391
(CHEMBL401976)Show InChI InChI=1S/C14H21N3O/c1-3-17(4-2)13(18)14(9-11(14)10-15)12-7-5-6-8-16-12/h5-8,11H,3-4,9-10,15H2,1-2H3/t11-,14-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373390
(CHEMBL402088)Show InChI InChI=1S/C14H21N3O/c1-3-17(4-2)13(18)14(8-12(14)9-15)11-6-5-7-16-10-11/h5-7,10,12H,3-4,8-9,15H2,1-2H3/t12-,14+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373404
(CHEMBL402090)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCCC=C1)c1ccsc1 |c:12| Show InChI InChI=1S/C14H18N2OS/c15-9-12-8-14(12,11-4-7-18-10-11)13(17)16-5-2-1-3-6-16/h2,4-5,7,10,12H,1,3,6,8-9,15H2/t12-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373394
(CHEMBL258013)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1sc(Cl)c(Cl)c1Cl Show InChI InChI=1S/C13H17Cl3N2OS/c1-3-18(4-2)12(19)13(5-7(13)6-17)10-8(14)9(15)11(16)20-10/h7H,3-6,17H2,1-2H3/t7-,13-/m0/s1 | PDB
KEGG
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DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373395
(CHEMBL401804)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C13H18Cl2N2OS/c1-3-17(4-2)12(18)13(6-8(13)7-16)10-5-9(14)11(15)19-10/h5,8H,3-4,6-7,16H2,1-2H3/t8-,13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373388
(CHEMBL403370)Show InChI InChI=1S/C16H21N3OS/c1-3-19(4-2)15(20)16(9-11(16)10-17)14-18-12-7-5-6-8-13(12)21-14/h5-8,11H,3-4,9-10,17H2,1-2H3/t11-,16-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373393
(CHEMBL257338)Show InChI InChI=1S/C17H22N2OS/c1-3-19(4-2)16(20)17(10-13(17)11-18)15-9-12-7-5-6-8-14(12)21-15/h5-9,13H,3-4,10-11,18H2,1-2H3/t13-,17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373387
(CHEMBL257808)Show InChI InChI=1S/C17H22N2OS/c1-3-19(4-2)16(20)17(9-12(17)10-18)14-11-21-15-8-6-5-7-13(14)15/h5-8,11-12H,3-4,9-10,18H2,1-2H3/t12-,17-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50032379
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
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| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373391
(CHEMBL401976)Show InChI InChI=1S/C14H21N3O/c1-3-17(4-2)13(18)14(9-11(14)10-15)12-7-5-6-8-16-12/h5-8,11H,3-4,9-10,15H2,1-2H3/t11-,14-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM86420
(CAS_92623-85-3 | Milnacipran | NSC_0)Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m1/s1 | PDB
KEGG
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| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373392
(CHEMBL403760)Show InChI InChI=1S/C14H22N2OS/c1-4-16(5-2)13(17)14(8-12(14)9-15-3)11-6-7-18-10-11/h6-7,10,12,15H,4-5,8-9H2,1-3H3/t12-,14+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373390
(CHEMBL402088)Show InChI InChI=1S/C14H21N3O/c1-3-17(4-2)13(18)14(8-12(14)9-15)11-6-5-7-16-10-11/h5-7,10,12H,3-4,8-9,15H2,1-2H3/t12-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373392
(CHEMBL403760)Show InChI InChI=1S/C14H22N2OS/c1-4-16(5-2)13(17)14(8-12(14)9-15-3)11-6-7-18-10-11/h6-7,10,12,15H,4-5,8-9H2,1-3H3/t12-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM86420
(CAS_92623-85-3 | Milnacipran | NSC_0)Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373397
(CHEMBL257809)Show InChI InChI=1S/C13H19BrN2OS/c1-3-16(4-2)12(17)13(7-9(13)8-15)10-5-6-11(14)18-10/h5-6,9H,3-4,7-8,15H2,1-2H3/t9-,13-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373402
(CHEMBL257348)Show SMILES NC[C@@H]1C[C@@]1(C(=O)C1NCc2ccccc12)c1ccsc1 |w:7.7| Show InChI InChI=1S/C17H18N2OS/c18-8-13-7-17(13,12-5-6-21-10-12)16(20)15-14-4-2-1-3-11(14)9-19-15/h1-6,10,13,15,19H,7-9,18H2/t13-,15?,17+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373386
(CHEMBL255663)Show InChI InChI=1S/C15H20N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h3-5,8,11,13H,1-2,6-7,9-10,16H2/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373388
(CHEMBL403370)Show InChI InChI=1S/C16H21N3OS/c1-3-19(4-2)15(20)16(9-11(16)10-17)14-18-12-7-5-6-8-13(12)21-14/h5-8,11H,3-4,9-10,17H2,1-2H3/t11-,16-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373405
(CHEMBL257389)Show InChI InChI=1S/C15H21FN2O2S/c1-11(16)9-18(4-5-20-2)14(19)15(7-13(15)8-17)12-3-6-21-10-12/h3,6,10,13H,1,4-5,7-9,17H2,2H3/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373399
(CHEMBL401677)Show SMILES CCN(C=C)C(=O)[C@]1(C[C@H]1CN)c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H22N2O3/c1-3-19(4-2)16(20)17(10-13(17)11-18)12-5-6-14-15(9-12)22-8-7-21-14/h3,5-6,9,13H,1,4,7-8,10-11,18H2,2H3/t13-,17+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373392
(CHEMBL403760)Show InChI InChI=1S/C14H22N2OS/c1-4-16(5-2)13(17)14(8-12(14)9-15-3)11-6-7-18-10-11/h6-7,10,12,15H,4-5,8-9H2,1-3H3/t12-,14+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373396
(CHEMBL257810)Show InChI InChI=1S/C13H19ClN2OS/c1-3-16(4-2)12(17)13(7-9(13)8-15)10-5-6-11(14)18-10/h5-6,9H,3-4,7-8,15H2,1-2H3/t9-,13-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373398
(CHEMBL401676)Show InChI InChI=1S/C13H20N2OS/c1-3-15(4-2)12(16)13(7-11(13)8-14)10-5-6-17-9-10/h5-6,9,11H,3-4,7-8,14H2,1-2H3/t11-,13+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373384
(CHEMBL403759)Show InChI InChI=1S/C15H24N2OS/c1-5-17(6-2)14(18)15(12-7-8-19-11-12)9-13(15)10-16(3)4/h7-8,11,13H,5-6,9-10H2,1-4H3/t13-,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373401
(CHEMBL255246)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCCc2ccccc12)c1ccsc1 Show InChI InChI=1S/C18H20N2OS/c19-11-15-10-18(15,14-7-9-22-12-14)17(21)20-8-3-5-13-4-1-2-6-16(13)20/h1-2,4,6-7,9,12,15H,3,5,8,10-11,19H2/t15-,18+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373404
(CHEMBL402090)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCCC=C1)c1ccsc1 |c:12| Show InChI InChI=1S/C14H18N2OS/c15-9-12-8-14(12,11-4-7-18-10-11)13(17)16-5-2-1-3-6-16/h2,4-5,7,10,12H,1,3,6,8-9,15H2/t12-,14+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373384
(CHEMBL403759)Show InChI InChI=1S/C15H24N2OS/c1-5-17(6-2)14(18)15(12-7-8-19-11-12)9-13(15)10-16(3)4/h7-8,11,13H,5-6,9-10H2,1-4H3/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373390
(CHEMBL402088)Show InChI InChI=1S/C14H21N3O/c1-3-17(4-2)13(18)14(8-12(14)9-15)11-6-5-7-16-10-11/h5-7,10,12H,3-4,8-9,15H2,1-2H3/t12-,14+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373394
(CHEMBL258013)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1sc(Cl)c(Cl)c1Cl Show InChI InChI=1S/C13H17Cl3N2OS/c1-3-18(4-2)12(19)13(5-7(13)6-17)10-8(14)9(15)11(16)20-10/h7H,3-6,17H2,1-2H3/t7-,13-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373388
(CHEMBL403370)Show InChI InChI=1S/C16H21N3OS/c1-3-19(4-2)15(20)16(9-11(16)10-17)14-18-12-7-5-6-8-13(12)21-14/h5-8,11H,3-4,9-10,17H2,1-2H3/t11-,16-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373395
(CHEMBL401804)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C13H18Cl2N2OS/c1-3-17(4-2)12(18)13(6-8(13)7-16)10-5-9(14)11(15)19-10/h5,8H,3-4,6-7,16H2,1-2H3/t8-,13-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373400
(CHEMBL402089)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1C=COc2ccccc12)c1ccsc1 |c:9| Show InChI InChI=1S/C17H16N2O2S/c18-10-13-9-17(13,12-5-8-22-11-12)16(20)19-6-7-21-15-4-2-1-3-14(15)19/h1-8,11,13H,9-10,18H2/t13-,17+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373403
(CHEMBL404027)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N1CCc2ccccc2C1)c1ccsc1 Show InChI InChI=1S/C18H20N2OS/c19-10-16-9-18(16,15-6-8-22-12-15)17(21)20-7-5-13-3-1-2-4-14(13)11-20/h1-4,6,8,12,16H,5,7,9-11,19H2/t16-,18+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373408
(CHEMBL439423)Show InChI InChI=1S/C13H16N2OS/c1-3-5-15(2)12(16)13(7-11(13)8-14)10-4-6-17-9-10/h1,4,6,9,11H,5,7-8,14H2,2H3/t11-,13+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373410
(CHEMBL255448)Show InChI InChI=1S/C13H20N2O2S/c1-15(4-5-17-2)12(16)13(7-11(13)8-14)10-3-6-18-9-10/h3,6,9,11H,4-5,7-8,14H2,1-2H3/t11-,13+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373411
(CHEMBL255449)Show InChI InChI=1S/C15H20N2OS/c1-2-6-17(13-3-4-13)14(18)15(8-12(15)9-16)11-5-7-19-10-11/h2,5,7,10,12-13H,1,3-4,6,8-9,16H2/t12-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373385
(CHEMBL255450)Show InChI InChI=1S/C15H18N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h1,4-5,8,11,13H,2,6-7,9-10,16H2/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50239791
((1S,2R)-N-allyl-2-(aminomethyl)-N-ethyl-1-(thiophe...)Show InChI InChI=1S/C14H20N2OS/c1-3-6-16(4-2)13(17)14(8-12(14)9-15)11-5-7-18-10-11/h3,5,7,10,12H,1,4,6,8-9,15H2,2H3/t12-,14+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373387
(CHEMBL257808)Show InChI InChI=1S/C17H22N2OS/c1-3-19(4-2)16(20)17(9-12(17)10-18)14-11-21-15-8-6-5-7-13(14)15/h5-8,11-12H,3-4,9-10,18H2,1-2H3/t12-,17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373384
(CHEMBL403759)Show InChI InChI=1S/C15H24N2OS/c1-5-17(6-2)14(18)15(12-7-8-19-11-12)9-13(15)10-16(3)4/h7-8,11,13H,5-6,9-10H2,1-4H3/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373406
(CHEMBL402027)Show InChI InChI=1S/C13H17FN2OS/c1-9(14)7-16(2)12(17)13(5-11(13)6-15)10-3-4-18-8-10/h3-4,8,11H,1,5-7,15H2,2H3/t11-,13+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373407
(CHEMBL257388)Show InChI InChI=1S/C15H16N2OS/c1-3-6-17(7-4-2)14(18)15(9-13(15)10-16)12-5-8-19-11-12/h1-2,5,8,11,13H,6-7,9-10,16H2/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50239784
((1R,2R)-2-(aminomethyl)-N,N-diethyl-1-(thiophen-2-...)Show InChI InChI=1S/C13H20N2OS/c1-3-15(4-2)12(16)13(8-10(13)9-14)11-6-5-7-17-11/h5-7,10H,3-4,8-9,14H2,1-2H3/t10-,13-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM86420
(CAS_92623-85-3 | Milnacipran | NSC_0)Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373389
(CHEMBL257130)Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1cc2cc(F)ccc2s1 Show InChI InChI=1S/C17H21FN2OS/c1-3-20(4-2)16(21)17(9-12(17)10-19)15-8-11-7-13(18)5-6-14(11)22-15/h5-8,12H,3-4,9-10,19H2,1-2H3/t12-,17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373409
(CHEMBL257390)Show InChI InChI=1S/C15H20N2O2S/c1-3-5-17(6-7-19-2)14(18)15(9-13(15)10-16)12-4-8-20-11-12/h1,4,8,11,13H,5-7,9-10,16H2,2H3/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373412
(CHEMBL403616)Show InChI InChI=1S/C15H22N2O2S/c1-3-5-17(6-7-19-2)14(18)15(9-13(15)10-16)12-4-8-20-11-12/h3-4,8,11,13H,1,5-7,9-10,16H2,2H3/t13-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373391
(CHEMBL401976)Show InChI InChI=1S/C14H21N3O/c1-3-17(4-2)13(18)14(9-11(14)10-15)12-7-5-6-8-16-12/h5-8,11H,3-4,9-10,15H2,1-2H3/t11-,14-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373413
(CHEMBL257603)Show InChI InChI=1S/C13H18N2OS/c1-3-5-15(2)12(16)13(7-11(13)8-14)10-4-6-17-9-10/h3-4,6,9,11H,1,5,7-8,14H2,2H3/t11-,13+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 3230-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8 |
More data for this
Ligand-Target Pair | |
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