Affinity Data by PubMed id=18547811

PubMed code 18547811

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50243051 (4-(Benzofuroxan-5-ylmethyloxy)benzaldehydeamidinoh...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50242897 (4-(Benzofuroxan-5-ylmethyloxy)benzaldehydethiosemi...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50243052 (2-[(Benzofuroxan-5-yl)methylene]-1-(2-hydroxybenzy...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50243054 (2-[(Benzofuroxan-5-yl)methylene]-1-(5-bromo-2-hydr...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50242827 (CHEMBL460050 \| N4-Phenyl benzofuroxan-5-carboxalde...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50242826 (4-Allyl-1-(N1-oxide-benzo[1,2-c][1,2,5]oxadiazole-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50242830 (4-(Benzofuroxan-5-ylmethyloxy)benzaldehydesemicarb...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50242825 (Benzofuroxan-5-carboxaldehyde thiosemicarbazone \| ...) Show SMILES NC(=S)N[N-][CH+]c1ccc2no[n+]([O-])c2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50243053 (2-[(Benzofuroxan-5-yl)methylene]-1-(4-hydroxybenzy...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Unviersidad de la República Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi Tulahuen 2 epimastigote cruzipain by spectrophotometry				Bioorg Med Chem 16: 6995-7004 (2008) Article DOI: 10.1016/j.bmc.2008.05.038 BindingDB Entry DOI: 10.7270/Q28G8KHQ
Unviersidad de la República Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%