Affinity Data by PubMed id=18569333

PubMed code 18569333

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86107 (Galanthamine, 7) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86103 (3'-Hydroxyepiglucoisatisin, 3) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86102 (Epiglucoisatisin, 2) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM50009001 (5,6,7-Trihydroxyflavone \| 5,6,7-trihydroxy-2-pheny...) Show SMILES Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86101 (2-[Cyano(3-indolyl) methylene]-3-indolone, 1) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86104 (Sulfoglucobrassicin, 4) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86103 (3'-Hydroxyepiglucoisatisin, 3) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86102 (Epiglucoisatisin, 2) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.37E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86101 (2-[Cyano(3-indolyl) methylene]-3-indolone, 1) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86104 (Sulfoglucobrassicin, 4) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86105 (Isatan A, 5) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.34E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86106 (Isatan B, 6) Show SMILES OCC1OC(Oc2c[nH]c3ccccc23)C(O)C(=O)C1O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.76E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description Butyrylcholinesterase activity-inhibiting activities were measured by a slightly modified spectrophotometric method developed by Ellman. DTNB was us...				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86105 (Isatan A, 5) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair
Linoleate 9S-lipoxygenase-4 (Glycine max (Soybean) (Glycine hispida))	BDBM86106 (Isatan B, 6) Show SMILES OCC1OC(Oc2c[nH]c3ccccc23)C(O)C(=O)C1O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.38E+4	n/a	n/a	n/a	n/a	8.0	25
PCSIR Laboratories Complex					Assay Description LOX inhibiting activity was measured by modifying the spectrophotometric method developed by Tappel.				J Enzyme Inhib Med Chem 23: 313-6 (2008) Article DOI: 10.1080/14756360701536455 BindingDB Entry DOI: 10.7270/Q2930RRD
PCSIR Laboratories Complex					More data for this Ligand-Target Pair

* indicates data uncertainty>20%