Affinity Data by PubMed id=18625553

PubMed code 18625553

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50262515 (CHEMBL453930 \| N-(4-bromo-2-oxo-2,5-dihydrofuran-3...) Show SMILES CCCCCC(=O)NC1=C(Br)COC1=O \|c:8\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSA Curated by ChEMBL					Assay Description Inhibition of LuxR-dependent Vibrio fischeri quorum sensing assessed as reduction in 3-oxo-hexanoyihomoserine-induced bioluminescence				Bioorg Med Chem Lett 18: 4321-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.090 BindingDB Entry DOI: 10.7270/Q23B5ZXK
INSA Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50262517 (CHEMBL448263 \| N-(4-chloro-2-oxo-2,5-dihydrofuran-...) Show SMILES CCCCCC(=O)NC1=C(Cl)COC1=O \|c:8\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSA Curated by ChEMBL					Assay Description Inhibition of LuxR-dependent Vibrio fischeri quorum sensing assessed as reduction in 3-oxo-hexanoyihomoserine-induced bioluminescence				Bioorg Med Chem Lett 18: 4321-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.090 BindingDB Entry DOI: 10.7270/Q23B5ZXK
INSA Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50262465 (3-oxo-N-(2-oxo-2,5-dihydrofuran-3-yl)hexanamide \| ...) Show SMILES CCCC(=O)CC(=O)NC1=CCOC1=O \|t:9\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Curated by ChEMBL					Assay Description Inhibition of LuxR-dependent Vibrio fischeri quorum sensing assessed as reduction in 3-oxo-hexanoyihomoserine-induced bioluminescence				Bioorg Med Chem Lett 18: 4321-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.090 BindingDB Entry DOI: 10.7270/Q23B5ZXK
INSA Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50262516 (CHEMBL478391 \| N-(4-bromo-2-oxo-2,5-dihydrofuran-3...) Show SMILES BrC1=C(NC(=O)CCCc2ccccc2)C(=O)OC1 \|c:1\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Curated by ChEMBL					Assay Description Inhibition of LuxR-dependent Vibrio fischeri quorum sensing assessed as reduction in 3-oxo-hexanoyihomoserine-induced bioluminescence				Bioorg Med Chem Lett 18: 4321-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.090 BindingDB Entry DOI: 10.7270/Q23B5ZXK
INSA Curated by ChEMBL					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50262464 (CHEMBL478634 \| N-(2-oxo-2,5-dihydrofuran-3-yl)hexa...) Show SMILES CCCCCC(=O)NC1=CCOC1=O \|t:8\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSA Curated by ChEMBL					Assay Description Inhibition of LuxR-dependent Vibrio fischeri quorum sensing assessed as reduction in 3-oxo-hexanoyihomoserine-induced bioluminescence				Bioorg Med Chem Lett 18: 4321-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.090 BindingDB Entry DOI: 10.7270/Q23B5ZXK
INSA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%