Affinity Data by PubMed id=18630892

PubMed code 18630892

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50261942 (6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol \| CHEMBL46...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 assessed as conversion of [3H]estrone to [3H]17beta-estradiol				J Med Chem 51: 4685-98 (2008) Article DOI: 10.1021/jm800367k BindingDB Entry DOI: 10.7270/Q29S1QVM
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50261887 (1-Bromo-6-(3-hydroxyphenyl)-2-naphthol \| CHEMBL467...) Show SMILES Oc1cccc(c1)-c1ccc2c(Br)c(O)ccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 assessed as conversion of [3H]estrone to [3H]17beta-estradiol				J Med Chem 51: 4685-98 (2008) Article DOI: 10.1021/jm800367k BindingDB Entry DOI: 10.7270/Q29S1QVM
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM50168371 (6-(3-Hydroxy-phenyl)-naphthalen-2-ol \| 6-(3-hydrox...) Show SMILES Oc1cccc(c1)-c1ccc2cc(O)ccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD1 assessed as conversion of [3H]estrone to [3H]17beta-estradiol				J Med Chem 51: 4685-98 (2008) Article DOI: 10.1021/jm800367k BindingDB Entry DOI: 10.7270/Q29S1QVM
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50261942 (6-(3-Hydroxyphenyl)-1-phenyl-2-naphthol \| CHEMBL46...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 assessed as conversion of [3H]17beta-estradiol to [3H]estrone				J Med Chem 51: 4685-98 (2008) Article DOI: 10.1021/jm800367k BindingDB Entry DOI: 10.7270/Q29S1QVM
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50261887 (1-Bromo-6-(3-hydroxyphenyl)-2-naphthol \| CHEMBL467...) Show SMILES Oc1cccc(c1)-c1ccc2c(Br)c(O)ccc2c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	639	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 assessed as conversion of [3H]17beta-estradiol to [3H]estrone				J Med Chem 51: 4685-98 (2008) Article DOI: 10.1021/jm800367k BindingDB Entry DOI: 10.7270/Q29S1QVM
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50168371 (6-(3-Hydroxy-phenyl)-naphthalen-2-ol \| 6-(3-hydrox...) Show SMILES Oc1cccc(c1)-c1ccc2cc(O)ccc2c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human placental 17beta-HSD2 assessed as conversion of [3H]17beta-estradiol to [3H]estrone				J Med Chem 51: 4685-98 (2008) Article DOI: 10.1021/jm800367k BindingDB Entry DOI: 10.7270/Q29S1QVM
Saarland University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%