Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25537 (4-(2-hydroxyethyl)-8-methyl-12,14-dioxa-8-azatetra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25539 (4-(2-methoxyethyl)-8-methyl-12,14-dioxa-8-azatetra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25538 (4-(methoxymethyl)-8-methyl-12,14-dioxa-8-azatetrac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25536 (4-(hydroxymethyl)-8-methyl-12,14-dioxa-8-azatetrac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25530 (8-methyl-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25540 (7,8-dihydroxy-5-methylphenanthridin-5-ium chloride...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25541 (7,8-dihydroxy-2-(hydroxymethyl)-5-methylphenanthri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25542 (7,8-dihydroxy-2-(2-hydroxyethyl)-5-methylphenanthr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25533 (8-oxido-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}....) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25529 (7,8-dimethoxy-5-methylphenanthridin-5-ium iodide |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25532 (7,8-dimethoxy-5-oxidophenanthridin-5-ium | chelery...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25524 (17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25528 (13,13-dimethyl-12,14-dioxa-8-azatetracyclo[8.7.0.0...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25535 (2-(hydroxymethyl)-7,8-dimethoxy-5-methylphenanthri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25526 (7,8-dimethoxyphenanthridine | chelerythrine analog...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25534 (13,13-dimethyl-8-oxido-12,14-dioxa-8-azatetracyclo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25527 (12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}.0^{11,15...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM25531 (8,13,13-trimethyl-12,14-dioxa-8-azatetracyclo[8.7....) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 22 |
A*STAR | Assay Description In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex... | J Med Chem 51: 6699-710 (2008) Article DOI: 10.1021/jm8005433 BindingDB Entry DOI: 10.7270/Q25M641R | |||||||||||
More data for this Ligand-Target Pair |