Affinity Data by PubMed id=18952425

PubMed code 18952425

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085290 (2-(4-Benzyl-phenoxy)-ethylamine \| 2-(4-benzylpheno...) Show SMILES NCCOc1ccc(Cc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as LTB4 production by R...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine \| CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as LTB4 production by R...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine \| CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246061 (4-(4-(pentyloxy)phenoxy)phenol \| CHEMBL500079) Show SMILES CCCCCOc1ccc(Oc2ccc(O)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246009 (1-(pentyloxy)-4-phenoxybenzene \| CHEMBL472892) Show SMILES CCCCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246011 (4-(4-butoxyphenoxy)phenol \| CHEMBL467374) Show SMILES CCCCOc1ccc(Oc2ccc(O)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246010 (4-(4-propoxyphenoxy)phenol \| CHEMBL472893) Show SMILES CCCOc1ccc(Oc2ccc(O)cc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246008 (1-butoxy-4-phenoxybenzene \| CHEMBL475731) Show SMILES CCCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%