Affinity Data by PubMed id=1895306

PubMed code 1895306

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009709 (4-Amino-5-butyl-1-(3-chloro-phenyl)-1,5-dihydro-py...) Show SMILES CCCCn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptor in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009707 (4-Amino-5-butyl-1-phenyl-1,5-dihydro-pyrazolo[3,4-...) Show SMILES CCCCn1c(N)c2cnn(-c3ccccc3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptor in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009708 (4-Amino-1-(3-chloro-phenyl)-5-propyl-1,5-dihydro-p...) Show SMILES CCCn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptor in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009704 (4-Amino-1-(3-chloro-phenyl)-5-methyl-1,5-dihydro-p...) Show SMILES Cn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptors in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009709 (4-Amino-5-butyl-1-(3-chloro-phenyl)-1,5-dihydro-py...) Show SMILES CCCCn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A2 receptors in rat striatal membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009705 (4-Amino-1,5-diphenyl-1,5-dihydro-pyrazolo[3,4-d]py...) Show SMILES CCn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptor in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009706 (4-Amino-5-ethyl-1-phenyl-1,5-dihydro-pyrazolo[3,4-...) Show SMILES CCn1c(N)c2cnn(-c3ccccc3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptor in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009705 (4-Amino-1,5-diphenyl-1,5-dihydro-pyrazolo[3,4-d]py...) Show SMILES CCn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A2 receptors in rat striatal membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009707 (4-Amino-5-butyl-1-phenyl-1,5-dihydro-pyrazolo[3,4-...) Show SMILES CCCCn1c(N)c2cnn(-c3ccccc3)c2nc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A2 receptors in rat striatal membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009708 (4-Amino-1-(3-chloro-phenyl)-5-propyl-1,5-dihydro-p...) Show SMILES CCCn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A2 receptors in rat striatal membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009710 (4-Amino-1-phenyl-5-propyl-1,5-dihydro-pyrazolo[3,4...) Show SMILES CCCn1c(N)c2cnn(-c3ccccc3)c2nc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A2 receptors in rat striatal membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009710 (4-Amino-1-phenyl-5-propyl-1,5-dihydro-pyrazolo[3,4...) Show SMILES CCCn1c(N)c2cnn(-c3ccccc3)c2nc1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptor in rat whole brain membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a/A2b (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009706 (4-Amino-5-ethyl-1-phenyl-1,5-dihydro-pyrazolo[3,4-...) Show SMILES CCn1c(N)c2cnn(-c3ccccc3)c2nc1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A2 receptors in rat striatal membrane				J Med Chem 34: 2892-8 (1991) BindingDB Entry DOI: 10.7270/Q2DJ5DMS
Griffith University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%