Affinity Data by PubMed id=19007110

PubMed code 19007110

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50275055 (4-{4-[2-(Phenyl-2-pyridinylamino)ethoxy]phenyl}but...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Agonist activity at human GPR120-Galpha16 fusion protein expressed in Flp-in HEK293 cells assessed as effect on intracellular calcium concentration b...				J Med Chem 51: 7640-4 (2009) Article DOI: 10.1021/jm800970b BindingDB Entry DOI: 10.7270/Q2862G9R
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50275158 (4-{4-[2-(phenyl-2-thiazolylamino)ethoxy]phenyl}but...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in T-REx HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assay				J Med Chem 51: 7640-4 (2009) Article DOI: 10.1021/jm800970b BindingDB Entry DOI: 10.7270/Q2862G9R
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50240347 ((9,12,15)-linolenic acid \| (9Z,12Z,15Z)-octadeca-9...) Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in T-REx HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assay				J Med Chem 51: 7640-4 (2009) Article DOI: 10.1021/jm800970b BindingDB Entry DOI: 10.7270/Q2862G9R
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50275055 (4-{4-[2-(Phenyl-2-pyridinylamino)ethoxy]phenyl}but...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in T-REx HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assay				J Med Chem 51: 7640-4 (2009) Article DOI: 10.1021/jm800970b BindingDB Entry DOI: 10.7270/Q2862G9R
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50240347 ((9,12,15)-linolenic acid \| (9Z,12Z,15Z)-octadeca-9...) Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Agonist activity at human GPR120-Galpha16 fusion protein expressed in Flp-in HEK293 cells assessed as effect on intracellular calcium concentration b...				J Med Chem 51: 7640-4 (2009) Article DOI: 10.1021/jm800970b BindingDB Entry DOI: 10.7270/Q2862G9R
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50275158 (4-{4-[2-(phenyl-2-thiazolylamino)ethoxy]phenyl}but...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description Agonist activity at human GPR120-Galpha16 fusion protein expressed in Flp-in HEK293 cells assessed as effect on intracellular calcium concentration b...				J Med Chem 51: 7640-4 (2009) Article DOI: 10.1021/jm800970b BindingDB Entry DOI: 10.7270/Q2862G9R
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%