Affinity Data by PubMed id=19053830

PubMed code 19053830

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50247135 (2-methyl-N-phenethyl-5-(phenylsulfonyl)benzenesulf...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.88E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assay				J Med Chem 51: 7670-2 (2008) Article DOI: 10.1021/jm801069w BindingDB Entry DOI: 10.7270/Q2N58M6D
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50246617 (2-Ethyl-5-(phenylsulfonyl)-N-(3-pyrrolidin-1-ylpro...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assay				J Med Chem 51: 7670-2 (2008) Article DOI: 10.1021/jm801069w BindingDB Entry DOI: 10.7270/Q2N58M6D
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50246616 (CHEMBL473916 \| N-[3-(Dimethylamino)propyl]-2-ethyl...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assay				J Med Chem 51: 7670-2 (2008) Article DOI: 10.1021/jm801069w BindingDB Entry DOI: 10.7270/Q2N58M6D
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50247135 (2-methyl-N-phenethyl-5-(phenylsulfonyl)benzenesulf...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to human sFRP1 by flurescence spectroscopy				J Med Chem 51: 7670-2 (2008) Article DOI: 10.1021/jm801069w BindingDB Entry DOI: 10.7270/Q2N58M6D
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50246651 (CHEMBL474926 \| N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.97E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assay				J Med Chem 51: 7670-2 (2008) Article DOI: 10.1021/jm801069w BindingDB Entry DOI: 10.7270/Q2N58M6D
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%