Affinity Data by PubMed id=19059783

PubMed code 19059783

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50254291 (2-(4-(Methylsulfonyl)phenyl)-N-(4-methoxyphenyl)-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of PGHS2 in human whole blood assessed as inhibition of TXB2 production by radioimmunoassay				Bioorg Med Chem 17: 74-84 (2008) Article DOI: 10.1016/j.bmc.2008.11.018 BindingDB Entry DOI: 10.7270/Q2TQ61DC
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of PGHS2 in human whole blood assessed as inhibition of TXB2 production by radioimmunoassay				Bioorg Med Chem 17: 74-84 (2008) Article DOI: 10.1016/j.bmc.2008.11.018 BindingDB Entry DOI: 10.7270/Q2TQ61DC
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50254238 (2-Phenyl-N-(2-pyridinyl)imidazo[1,2-a]pyridin-3-am...) Show SMILES N(c1c(nc2ccccn12)-c1ccccn1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Federal University of Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of PGHS2 in human whole blood assessed as inhibition of TXB2 production by radioimmunoassay				Bioorg Med Chem 17: 74-84 (2008) Article DOI: 10.1016/j.bmc.2008.11.018 BindingDB Entry DOI: 10.7270/Q2TQ61DC
Federal University of Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%