Affinity Data by PubMed id=19090779

PubMed code 19090779

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine \| CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISA				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine \| CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometry				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine \| CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human nonpancreatic secretory phospholipase A2				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50247069 (2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine \| CHEMBL...) Show SMILES NCCc1c[nH]c2c(OCc3ccccc3)cccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometry				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) Show SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometry				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50247034 (4-(4-Nitro-benzyl)-1-(2-oxo-2-phenyl-ethyl)-pyridi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometry				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) Show SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human nonpancreatic secretory phospholipase A2				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50247034 (4-(4-Nitro-benzyl)-1-(2-oxo-2-phenyl-ethyl)-pyridi...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human nonpancreatic secretory phospholipase A2				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50247069 (2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine \| CHEMBL...) Show SMILES NCCc1c[nH]c2c(OCc3ccccc3)cccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human nonpancreatic secretory phospholipase A2				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50247069 (2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine \| CHEMBL...) Show SMILES NCCc1c[nH]c2c(OCc3ccccc3)cccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISA				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50247033 (2-amino-3-(5-(benzyloxy)-1H-indol-3-yl)propanoic a...) Show SMILES NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISA				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50247034 (4-(4-Nitro-benzyl)-1-(2-oxo-2-phenyl-ethyl)-pyridi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.86E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISA				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%