Affinity Data by PubMed id=19135376

PubMed code 19135376

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056999 (CHEMBL56367 \| nimesulide) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of COX2 in LPS-stimulated human whole blood assessed as TXB2 production by enzyme immunoassay				Bioorg Med Chem 17: 1125-31 (2009) Article DOI: 10.1016/j.bmc.2008.12.045 BindingDB Entry DOI: 10.7270/Q2B56JMD
Universidade Federal do Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50255143 (CHEMBL482199 \| N-(6-(2-benzylidenehydrazinecarbony...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassay				Bioorg Med Chem 17: 1125-31 (2009) Article DOI: 10.1016/j.bmc.2008.12.045 BindingDB Entry DOI: 10.7270/Q2B56JMD
Universidade Federal do Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50255143 (CHEMBL482199 \| N-(6-(2-benzylidenehydrazinecarbony...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of COX2 in LPS-stimulated human whole blood assessed as TXB2 production by enzyme immunoassay				Bioorg Med Chem 17: 1125-31 (2009) Article DOI: 10.1016/j.bmc.2008.12.045 BindingDB Entry DOI: 10.7270/Q2B56JMD
Universidade Federal do Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50056999 (CHEMBL56367 \| nimesulide) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassay				Bioorg Med Chem 17: 1125-31 (2009) Article DOI: 10.1016/j.bmc.2008.12.045 BindingDB Entry DOI: 10.7270/Q2B56JMD
Universidade Federal do Rio de Janeiro Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%