Affinity Data by PubMed id=19136257

PubMed code 19136257

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transcription factor p65 (Homo sapiens (Human))	BDBM50277067 (1-(8-chloro-5-methoxy-2-(thiophen-2-yl)quinazolin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Potentiation of TNFalpha-induced NFkappaB p65 nuclear translocation in HUVEC cells by immunostaining				Bioorg Med Chem Lett 19: 1191-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.086 BindingDB Entry DOI: 10.7270/Q26H4H8Z
Columbia University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50135483 (1-(6-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Potentiation of TNFalpha-induced NFkappaB p65 nuclear translocation in HUVEC cells by immunostaining				Bioorg Med Chem Lett 19: 1191-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.086 BindingDB Entry DOI: 10.7270/Q26H4H8Z
Columbia University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50135483 (1-(6-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Induction of NFkappaB p65 nuclear translocation in HUVEC cells by immunostaining				Bioorg Med Chem Lett 19: 1191-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.086 BindingDB Entry DOI: 10.7270/Q26H4H8Z
Columbia University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50135482 (1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Induction of NFkappaB p65 nuclear translocation in HUVEC cells by immunostaining				Bioorg Med Chem Lett 19: 1191-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.086 BindingDB Entry DOI: 10.7270/Q26H4H8Z
Columbia University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50277067 (1-(8-chloro-5-methoxy-2-(thiophen-2-yl)quinazolin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Induction of NFkappaB p65 nuclear translocation in HUVEC cells by immunostaining				Bioorg Med Chem Lett 19: 1191-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.086 BindingDB Entry DOI: 10.7270/Q26H4H8Z
Columbia University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor p65 (Homo sapiens (Human))	BDBM50135482 (1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Potentiation of TNFalpha-induced NFkappaB p65 nuclear translocation in HUVEC cells by immunostaining				Bioorg Med Chem Lett 19: 1191-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.086 BindingDB Entry DOI: 10.7270/Q26H4H8Z
Columbia University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%