Affinity Data by PubMed id=19157884

PubMed code 19157884

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50276976 (2-(4-benzylpiperidin-1-yl)-1-(5-hydroxy-1Hindol-3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA NR2B receptor in Wistar rat cerebral cortex membrane				Bioorg Med Chem 17: 1640-7 (2009) Article DOI: 10.1016/j.bmc.2008.12.058 BindingDB Entry DOI: 10.7270/Q2D21XGV
Università di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50007674 ((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA NR2B receptor in Wistar rat cerebral cortex membrane				Bioorg Med Chem 17: 1640-7 (2009) Article DOI: 10.1016/j.bmc.2008.12.058 BindingDB Entry DOI: 10.7270/Q2D21XGV
Università di Messina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50276976 (2-(4-benzylpiperidin-1-yl)-1-(5-hydroxy-1Hindol-3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA NR2B receptor in Wistar rat cerebral cortex membrane				Bioorg Med Chem 17: 1640-7 (2009) Article DOI: 10.1016/j.bmc.2008.12.058 BindingDB Entry DOI: 10.7270/Q2D21XGV
Università di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50277043 (2-(4-benzylpiperidin-1-yl)-1-(1H-indol-3-yl)ethano...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	769	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA NR2B receptor in Wistar rat cerebral cortex membrane				Bioorg Med Chem 17: 1640-7 (2009) Article DOI: 10.1016/j.bmc.2008.12.058 BindingDB Entry DOI: 10.7270/Q2D21XGV
Università di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50276978 (1-(4-benzylpiperidin-1-yl)-2-(5-hydroxy-1Hindol-3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA NR2B receptor in Wistar rat cerebral cortex membrane				Bioorg Med Chem 17: 1640-7 (2009) Article DOI: 10.1016/j.bmc.2008.12.058 BindingDB Entry DOI: 10.7270/Q2D21XGV
Università di Messina Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%