Affinity Data by PubMed id=19195883

PubMed code 19195883

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50182369 (4-(2-(4-fluorophenyl)-7-(1-methylpiperidin-4-yl)H-...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0440	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248496 (2-(4-(2-(4-fluorophenyl)-3-(pyridin-4-yl)-1H-indol...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248450 (2-(4-fluorophenyl)-6-(piperidin-4-yl)-3-(pyridin-4...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248451 (2-(4-fluorophenyl)-6-(1-methylpiperidin-4-yl)-3-(p...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248452 (6-(1-ethylpiperidin-4-yl)-2-(4-fluorophenyl)-3-(py...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248396 (4-(2-(4-fluorophenyl)-6-(piperidin-4-yl)-1H-indol-...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248543 (4-(2-(4-fluorophenyl)-6-(1-methylpiperidin-4-yl)-1...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248397 (2-(4-(3-(2-aminopyrimidin-4-yl)-2-(4-fluorophenyl)...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248399 (2-(4-fluorophenyl)-6-(1-methylpiperidin-4-yl)-3-(p...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248498 (2-(4-fluorophenyl)-6-(1-methylazetidin-3-yl)-3-(py...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248398 (2-(4-fluorophenyl)-6-(piperidin-4-yl)-3-(pyrimidin...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248449 (2-(4-(2-(4-fluorophenyl)-3-(pyrimidin-4-yl)-1H-ind...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248499 (2-(4-fluorophenyl)-6-((1-methylpiperidin-4-yl)meth...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248542 (2-(4-fluorophenyl)-6-((4-methylpiperazin-1-yl)meth...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248497 (4-(2-(4-fluorophenyl)-3-(pyridin-4-yl)-1H-indol-6-...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50248541 ((2-(4-fluorophenyl)-3-(pyridin-4-yl)-1H-indol-6-yl...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella parasite-specific cGMP-dependent protein kinase				Bioorg Med Chem Lett 19: 1517-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.001 BindingDB Entry DOI: 10.7270/Q2WW7HJP
SCYNEXIS, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%