Affinity Data by PubMed id=19217289

PubMed code 19217289

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50248005 (1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50247982 (1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50247981 (1-(2-((S)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50247980 (1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50247980 (1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50247979 (1-(2-(3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquino...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50248006 (1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50247980 (1-(2-((R)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoq...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 1767-72 (2009) Article DOI: 10.1016/j.bmcl.2009.01.071 BindingDB Entry DOI: 10.7270/Q2Q52PHM
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%