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PubMed code 19217777

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50266829
PNG
(2-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-...)
Show SMILES Clc1cccc(N2CCN(CCCCN3CCCc4ccccc4C3=O)CC2)c1Cl
Show InChI InChI=1S/C24H29Cl2N3O/c25-21-10-5-11-22(23(21)26)28-17-15-27(16-18-28)12-3-4-13-29-14-6-8-19-7-1-2-9-20(19)24(29)30/h1-2,5,7,9-11H,3-4,6,8,12-18H2
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PC cid
PC sid
UniChem
Article
PubMed
10n/an/an/an/an/an/an/an/a



Universidad de Santiago de Compostela

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)


Bioorg Med Chem Lett 19: 1773-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.067
BindingDB Entry DOI: 10.7270/Q29W0FCP
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50266828
PNG
(2-(4-(4-(4-methoxyphenyl)piperazin-1-yl)butyl)-2,3...)
Show SMILES COc1ccc(cc1)N1CCN(CCCCN2CCCc3ccccc3C2=O)CC1
Show InChI InChI=1S/C25H33N3O2/c1-30-23-12-10-22(11-13-23)27-19-17-26(18-20-27)14-4-5-15-28-16-6-8-21-7-2-3-9-24(21)25(28)29/h2-3,7,9-13H,4-6,8,14-20H2,1H3
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antibodypedia
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PC cid
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UniChem

Similars

Article
PubMed
40n/an/an/an/an/an/an/an/a



Universidad de Santiago de Compostela

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human dopamine D3 receptor


Bioorg Med Chem Lett 19: 1773-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.067
BindingDB Entry DOI: 10.7270/Q29W0FCP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%