Affinity Data by PubMed id=19253982

PubMed code 19253982

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241111 (3-(2-Amino-4-fluoro-phenylamino)-6H-dibenzo[b,e]ox...) Show SMILES Nc1cc(F)ccc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241112 (2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]...) Show SMILES Nc1ccccc1Nc1ccc2c(CCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248859 (2-(2,4-Difluoro-phenylamino)-10,11-dihydro-dibenzo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248858 (2-(2-Amino-4-fluoro-phenylamino)-10,11-dihydro-dib...) Show SMILES Nc1cc(F)ccc1Nc1ccc2c(CCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248941 (8-(2,4-Difluoro-phenylamino)-11H-10-oxa-1-aza-dibe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248913 (8-(2,4-Difluoro-phenylamino)-10,11-dihydro-benzo[4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241114 (3-(2,4-Difluoro-phenylamino)-6H-dibenzo[b,e]oxepin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241115 (3-(2-Amino-phenylamino)-6H-dibenzo[b,e]oxepin-11-o...) Show SMILES Nc1ccccc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248890 (8-(2-Amino-phenylamino)-10,11-dihydro-benzo[4,5]cy...) Show SMILES Nc1ccccc1Nc1ccc2c(CCc3ncccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248889 (8-(2,4-Difluoro-phenylamino)-benzo[4,5]cyclohepta[...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248915 (8-(2-Amino-phenylamino)-5,6-dihydro-benzo[5,6]cycl...) Show SMILES Nc1ccccc1Nc1ccc2c(CCc3cccnc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241113 (2-(2-amino-phenylamino)-dibenzo[a,d]cyclohepten-5-...) Show SMILES Nc1ccccc1Nc1ccc2c(c1)ccc1ccccc1c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248888 (8-(2-Amino-phenylamino)-benzo[4,5]cyclohepta[1,2-b...) Show SMILES Nc1ccccc1Nc1ccc2c(c1)ccc1ncccc1c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248891 (8-(2-Amino-4-fluoro-phenylamino)-10,11-dihydro-ben...) Show SMILES Nc1cc(F)ccc1Nc1ccc2c(CCc3ncccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248914 (8-(2-Amino-phenylamino)-benzo[5,6]cyclohepta[1,2-c...) Show SMILES Nc1ccccc1Nc1ccc2c(c1)ccc1ccncc1c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248887 (2-(2,4-Difluoro-phenylamino)-dibenzo[a,d]cyclohept...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248939 (8-(2-Amino-phenylamino)-11H-10-oxa-1-aza-dibenzo[a...) Show SMILES Nc1ccccc1Nc1ccc2c(OCc3ncccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50248940 (8-(2-Amino-4-fluoro-phenylamino)-11H-10-oxa-1-aza-...) Show SMILES Nc1cc(F)ccc1Nc1ccc2c(OCc3ncccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assay				J Med Chem 52: 1778-82 (2009) Article DOI: 10.1021/jm801291f BindingDB Entry DOI: 10.7270/Q21836C7
Eberhard-Karls-Universität Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%