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PubMed code 19389627

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM81356
PNG
(PF-3845, 10)
Show SMILES FC(F)(F)c1ccc(Oc2cccc(CC3CCN(CC3)C(=O)Nc3cccnc3)c2)nc1
Show InChI InChI=1S/C24H23F3N4O2/c25-24(26,27)19-6-7-22(29-15-19)33-21-5-1-3-18(14-21)13-17-8-11-31(12-9-17)23(32)30-20-4-2-10-28-16-20/h1-7,10,14-17H,8-9,11-13H2,(H,30,32)
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MCE
PC cid
PC sid
PDB
UniChem
Article
PubMed
230n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
Enzyme-coupled assay using oleamide as substrate where stoichiometic quantites of NAD are formed upon the generation of ammonia from oleamide by FAAH...


Chem Biol 16: 411-20 (2009)


Article DOI: 10.1016/j.chembiol.2009.02.013
BindingDB Entry DOI: 10.7270/Q2S180ZP
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM26739
PNG
(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1
Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
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CHEMBL
MCE
PC cid
PC sid
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Similars

Article
PubMed
2.00E+3n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
Enzyme-coupled assay using oleamide as substrate where stoichiometic quantites of NAD are formed upon the generation of ammonia from oleamide by FAAH...


Chem Biol 16: 411-20 (2009)


Article DOI: 10.1016/j.chembiol.2009.02.013
BindingDB Entry DOI: 10.7270/Q2S180ZP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%