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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50293657 (4,4'-(hex-3-ene-3,4-diyl)bis(2-((diethylamino)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Semmelweis University Curated by ChEMBL | Assay Description Inhibition of recombinant JAK2-Val617Phe kinase activity after 30 mins by luminometry | Bioorg Med Chem Lett 19: 3598-601 (2009) Article DOI: 10.1016/j.bmcl.2009.04.138 BindingDB Entry DOI: 10.7270/Q2D79BF4 | |||||||||||
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