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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31272 (NSC 333003 | NSC-333003) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 24 |
H. Lee Moffitt Cancer Center | Assay Description When two proteins interact (one of which is conjugated to the donor bead and the other to the acceptor bead) the beads are brought into close proximi... | Bioorg Med Chem Lett 19: 3756-9 (2009) Article DOI: 10.1016/j.bmcl.2009.04.124 BindingDB Entry DOI: 10.7270/Q2MC8XC4 | |||||||||||
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