Affinity Data by PubMed id=19540763

PubMed code 19540763

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of COX1-mediated PGH2 production by enzyme immunoassay				Bioorg Med Chem 17: 5044-53 (2009) Article DOI: 10.1016/j.bmc.2009.05.065 BindingDB Entry DOI: 10.7270/Q2X92BCX
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of COX2-mediated PGH2 production by enzyme immunoassay				Bioorg Med Chem 17: 5044-53 (2009) Article DOI: 10.1016/j.bmc.2009.05.065 BindingDB Entry DOI: 10.7270/Q2X92BCX
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Delta-type opioid receptor (MOUSE)	BDBM50300853 (CHEMBL568473 \| [2-Methyl-1-(1-benzyl-piperidin-4-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at delta opioid receptor in ICR mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction at 1 uM				Bioorg Med Chem 17: 5044-53 (2009) Article DOI: 10.1016/j.bmc.2009.05.065 BindingDB Entry DOI: 10.7270/Q2X92BCX
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50300853 (CHEMBL568473 \| [2-Methyl-1-(1-benzyl-piperidin-4-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor in Hartley guinea pig ileum/longitudinal muscle with myenteric plexus assessed as inhibition of electrically-s...				Bioorg Med Chem 17: 5044-53 (2009) Article DOI: 10.1016/j.bmc.2009.05.065 BindingDB Entry DOI: 10.7270/Q2X92BCX
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%