Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294161 ((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294161 ((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294162 ((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294163 ((R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 157 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294162 ((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294163 ((R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294164 (1-(2,2'-bithiophen-5-yl)methanamine | 2,2'-bithiop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 3.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294164 (1-(2,2'-bithiophen-5-yl)methanamine | 2,2'-bithiop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 7.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294165 ((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 1.06E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294165 ((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 1.06E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50085531 (3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294166 (CHEMBL558285 | pyridin-4-yl(4-(2-(pyrrolidin-1-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294166 (CHEMBL558285 | pyridin-4-yl(4-(2-(pyrrolidin-1-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294167 (5-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole | CHEMBL56...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50085531 (3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.47E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM13337 (3-(benzyloxy)pyridin-2-amine | EN300-247019 | Pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 3.08E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294167 (5-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole | CHEMBL56...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 3.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM13337 (3-(benzyloxy)pyridin-2-amine | EN300-247019 | Pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 6.19E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294168 (1-(2-(1H-indol-5-yloxy)ethyl)piperidine-4-carboxyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | 9.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294170 (5-fluoro-1H-indole | CHEMBL555457) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294169 (5-chloro-1H-indole | CHEMBL555013) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM32212 (1H-indol-5-ol | cid_16054) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50293592 (4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294171 (CHEMBL549343 | N-methyl-1-(2-(thiophen-2-yl)phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | 1.08E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294172 (CHEMBL264669 | N-(pyridin-3-ylmethyl)aniline | N-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.32E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50293592 (4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | 1.44E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294168 (1-(2-(1H-indol-5-yloxy)ethyl)piperidine-4-carboxyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | 1.49E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294169 (5-chloro-1H-indole | CHEMBL555013) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 1.51E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294172 (CHEMBL264669 | N-(pyridin-3-ylmethyl)aniline | N-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.67E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM32212 (1H-indol-5-ol | cid_16054) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294171 (CHEMBL549343 | N-methyl-1-(2-(thiophen-2-yl)phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294170 (5-fluoro-1H-indole | CHEMBL555457) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB Article PubMed | n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294173 ((4-fluorophenyl)(pyridin-4-yl)methanone | CHEMBL56...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 3.67E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50294173 ((4-fluorophenyl)(pyridin-4-yl)methanone | CHEMBL56...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 5.31E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE biostructures, Inc. Curated by ChEMBL | Assay Description Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo... | J Med Chem 52: 4694-715 (2009) Article DOI: 10.1021/jm900259h BindingDB Entry DOI: 10.7270/Q2F47P6N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |