BindingDB logo
myBDB logout

PubMed code 19620011

Compile data set for download or QSAR
Found 80 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM13211
PNG
((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1CCC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C27H34N4O3/c1-2-21(28)25(32)29-22-15-9-14-20-16-17-23(31(20)27(22)34)26(33)30-24(18-10-5-3-6-11-18)19-12-7-4-8-13-19/h3-8,10-13,20-24H,2,9,14-17,28H2,1H3,(H,29,32)(H,30,33)/t20-,21-,22-,23-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 25 -43.1 460n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM13212
PNG
((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1CCC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H36N4O3/c1-3-22(29-2)26(33)30-23-16-10-15-21-17-18-24(32(21)28(23)35)27(34)31-25(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,21-25,29H,3,10,15-18H2,1-2H3,(H,30,33)(H,31,34)/t21-,22-,23-,24-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 61 -40.9 530n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32615
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 40d)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H45N5O3/c1-3-30(37-2)34(42)40-33-28(24-38-23-25-13-7-4-8-14-25)19-20-29-21-22-31(41(29)36(33)44)35(43)39-32(26-15-9-5-10-16-26)27-17-11-6-12-18-27/h4-18,28-33,37-38H,3,19-24H2,1-2H3,(H,39,43)(H,40,42)/t28-,29+,30+,31+,33+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32589
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H43N5O3/c1-2-29(36)33(41)39-32-27(23-37-22-24-12-6-3-7-13-24)18-19-28-20-21-30(40(28)35(32)43)34(42)38-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32,37H,2,18-23,36H2,1H3,(H,38,42)(H,39,41)/t27-,28+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 35n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32589
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H43N5O3/c1-2-29(36)33(41)39-32-27(23-37-22-24-12-6-3-7-13-24)18-19-28-20-21-30(40(28)35(32)43)34(42)38-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32,37H,2,18-23,36H2,1H3,(H,38,42)(H,39,41)/t27-,28+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 49n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32603
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 28b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(N)=S)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N6O3S/c1-2-22(30)26(36)34-25-20(17-32-29(31)39)13-14-21-15-16-23(35(21)28(25)38)27(37)33-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,30H2,1H3,(H,33,37)(H,34,36)(H3,31,32,39)/t20-,21+,22+,23+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32582
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 4b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N5O3/c1-3-23(31-2)27(35)33-26-21(18-30)14-15-22-16-17-24(34(22)29(26)37)28(36)32-25(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,21-26,31H,3,14-18,30H2,1-2H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32601
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26d)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=S)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H44N6O3S/c1-2-29(37)33(43)41-32-27(23-39-36(46)38-22-24-12-6-3-7-13-24)18-19-28-20-21-30(42(28)35(32)45)34(44)40-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32H,2,18-23,37H2,1H3,(H,40,44)(H,41,43)(H2,38,39,46)/t27-,28+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32609
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H43N5O4/c1-3-29(37-2)34(43)40-32-27(23-38-33(42)26-17-11-6-12-18-26)19-20-28-21-22-30(41(28)36(32)45)35(44)39-31(24-13-7-4-8-14-24)25-15-9-5-10-16-25/h4-18,27-32,37H,3,19-23H2,1-2H3,(H,38,42)(H,39,44)(H,40,43)/t27-,28+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 55n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32588
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18a | 1-...)
Show SMILES CCNC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H41N5O3/c1-3-24(31)28(36)34-27-22(19-32-4-2)15-16-23-17-18-25(35(23)30(27)38)29(37)33-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27,32H,3-4,15-19,31H2,1-2H3,(H,33,37)(H,34,36)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 56n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32595
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22c | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H41N5O4/c1-2-28(36)33(42)39-31-26(22-37-32(41)25-16-10-5-11-17-25)18-19-27-20-21-29(40(27)35(31)44)34(43)38-30(23-12-6-3-7-13-23)24-14-8-4-9-15-24/h3-17,26-31H,2,18-22,36H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t26-,27+,28+,29+,31+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 58n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32611
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 38b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNC(=O)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C37H46N6O4/c1-3-30(38-2)34(44)42-33-28(24-40-37(47)39-23-25-13-7-4-8-14-25)19-20-29-21-22-31(43(29)36(33)46)35(45)41-32(26-15-9-5-10-16-26)27-17-11-6-12-18-27/h4-18,28-33,38H,3,19-24H2,1-2H3,(H,41,45)(H,42,44)(H2,39,40,47)/t28-,29+,30+,31+,33+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32606
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 34a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CCO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N4O4/c1-2-23(30)27(35)32-26-21(17-18-34)13-14-22-15-16-24(33(22)29(26)37)28(36)31-25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-26,34H,2,13-18,30H2,1H3,(H,31,36)(H,32,35)/t21-,22+,23+,24+,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32613
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 40b)
Show SMILES CCNC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@H](CC)NC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C31H43N5O3/c1-4-25(32-3)29(37)35-28-23(20-33-5-2)16-17-24-18-19-26(36(24)31(28)39)30(38)34-27(21-12-8-6-9-13-21)22-14-10-7-11-15-22/h6-15,23-28,32-33H,4-5,16-20H2,1-3H3,(H,34,38)(H,35,37)/t23-,24+,25+,26+,28+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32589
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H43N5O3/c1-2-29(36)33(41)39-32-27(23-37-22-24-12-6-3-7-13-24)18-19-28-20-21-30(40(28)35(32)43)34(42)38-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32,37H,2,18-23,36H2,1H3,(H,38,42)(H,39,41)/t27-,28+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 72n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32599
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H44N6O4/c1-2-29(37)33(43)41-32-27(23-39-36(46)38-22-24-12-6-3-7-13-24)18-19-28-20-21-30(42(28)35(32)45)34(44)40-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32H,2,18-23,37H2,1H3,(H,40,44)(H,41,43)(H2,38,39,46)/t27-,28+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 75n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32600
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26c)
Show SMILES CCNC(=S)NC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C31H42N6O3S/c1-3-24(32)28(38)36-27-22(19-34-31(41)33-4-2)15-16-23-17-18-25(37(23)30(27)40)29(39)35-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27H,3-4,15-19,32H2,1-2H3,(H,35,39)(H,36,38)(H2,33,34,41)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 83n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32605
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 32b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CCN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H41N5O3/c1-3-24(32-2)28(36)34-27-22(18-19-31)14-15-23-16-17-25(35(23)30(27)38)29(37)33-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27,32H,3,14-19,31H2,1-2H3,(H,33,37)(H,34,36)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 85n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32613
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 40b)
Show SMILES CCNC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@H](CC)NC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C31H43N5O3/c1-4-25(32-3)29(37)35-28-23(20-33-5-2)16-17-24-18-19-26(36(24)31(28)39)30(38)34-27(21-12-8-6-9-13-21)22-14-10-7-11-15-22/h6-15,23-28,32-33H,4-5,16-20H2,1-3H3,(H,34,38)(H,35,37)/t23-,24+,25+,26+,28+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 86n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM26205
PNG
((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(2-ami...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CCN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N5O3/c1-2-23(31)27(35)33-26-21(17-18-30)13-14-22-15-16-24(34(22)29(26)37)28(36)32-25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-26H,2,13-18,30-31H2,1H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 86n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32588
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18a | 1-...)
Show SMILES CCNC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H41N5O3/c1-3-24(31)28(36)34-27-22(19-32-4-2)15-16-23-17-18-25(35(23)30(27)38)29(37)33-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27,32H,3-4,15-19,31H2,1-2H3,(H,33,37)(H,34,36)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 92n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32599
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H44N6O4/c1-2-29(37)33(43)41-32-27(23-39-36(46)38-22-24-12-6-3-7-13-24)18-19-28-20-21-30(42(28)35(32)45)34(44)40-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32H,2,18-23,37H2,1H3,(H,40,44)(H,41,43)(H2,38,39,46)/t27-,28+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 97n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32611
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 38b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNC(=O)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C37H46N6O4/c1-3-30(38-2)34(44)42-33-28(24-40-37(47)39-23-25-13-7-4-8-14-25)19-20-29-21-22-31(43(29)36(33)46)35(45)41-32(26-15-9-5-10-16-26)27-17-11-6-12-18-27/h4-18,28-33,38H,3,19-24H2,1-2H3,(H,41,45)(H,42,44)(H2,39,40,47)/t28-,29+,30+,31+,33+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32582
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 4b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N5O3/c1-3-23(31-2)27(35)33-26-21(18-30)14-15-22-16-17-24(34(22)29(26)37)28(36)32-25(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,21-26,31H,3,14-18,30H2,1-2H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 100n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32607
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 34b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CCO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H40N4O4/c1-3-24(31-2)28(36)33-27-22(18-19-35)14-15-23-16-17-25(34(23)30(27)38)29(37)32-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27,31,35H,3,14-19H2,1-2H3,(H,32,37)(H,33,36)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32592
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 20c)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN(CC)CC)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C32H45N5O3/c1-4-26(33)30(38)35-29-24(21-36(5-2)6-3)17-18-25-19-20-27(37(25)32(29)40)31(39)34-28(22-13-9-7-10-14-22)23-15-11-8-12-16-23/h7-16,24-29H,4-6,17-21,33H2,1-3H3,(H,34,39)(H,35,38)/t24-,25+,26+,27+,29+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32591
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 20b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN(CC)Cc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C37H47N5O3/c1-3-31(38)35(43)40-34-29(25-41(4-2)24-26-14-8-5-9-15-26)20-21-30-22-23-32(42(30)37(34)45)36(44)39-33(27-16-10-6-11-17-27)28-18-12-7-13-19-28/h5-19,29-34H,3-4,20-25,38H2,1-2H3,(H,39,44)(H,40,43)/t29-,30+,31+,32+,34+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32615
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 40d)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H45N5O3/c1-3-30(37-2)34(42)40-33-28(24-38-23-25-13-7-4-8-14-25)19-20-29-21-22-31(41(29)36(33)44)35(43)39-32(26-15-9-5-10-16-26)27-17-11-6-12-18-27/h4-18,28-33,37-38H,3,19-24H2,1-2H3,(H,39,43)(H,40,42)/t28-,29+,30+,31+,33+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM26204
PNG
((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(amino...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H37N5O3/c1-2-22(30)26(34)32-25-20(17-29)13-14-21-15-16-23(33(21)28(25)36)27(35)31-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,29-30H2,1H3,(H,31,35)(H,32,34)/t20-,21+,22+,23+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32595
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22c | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H41N5O4/c1-2-28(36)33(42)39-31-26(22-37-32(41)25-16-10-5-11-17-25)18-19-27-20-21-29(40(27)35(31)44)34(43)38-30(23-12-6-3-7-13-23)24-14-8-4-9-15-24/h3-17,26-31H,2,18-22,36H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t26-,27+,28+,29+,31+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32588
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18a | 1-...)
Show SMILES CCNC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H41N5O3/c1-3-24(31)28(36)34-27-22(19-32-4-2)15-16-23-17-18-25(35(23)30(27)38)29(37)33-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27,32H,3-4,15-19,31H2,1-2H3,(H,33,37)(H,34,36)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32609
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 36b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H43N5O4/c1-3-29(37-2)34(43)40-32-27(23-38-33(42)26-17-11-6-12-18-26)19-20-28-21-22-30(41(28)36(32)45)35(44)39-31(24-13-7-4-8-14-24)25-15-9-5-10-16-25/h4-18,27-32,37H,3,19-23H2,1-2H3,(H,38,42)(H,39,44)(H,40,43)/t27-,28+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32595
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22c | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H41N5O4/c1-2-28(36)33(42)39-31-26(22-37-32(41)25-16-10-5-11-17-25)18-19-27-20-21-29(40(27)35(31)44)34(43)38-30(23-12-6-3-7-13-23)24-14-8-4-9-15-24/h3-17,26-31H,2,18-22,36H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t26-,27+,28+,29+,31+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32607
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 34b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CCO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H40N4O4/c1-3-24(31-2)28(36)33-27-22(18-19-35)14-15-23-16-17-25(34(23)30(27)38)29(37)32-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27,31,35H,3,14-19H2,1-2H3,(H,32,37)(H,33,36)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32605
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 32b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CCN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H41N5O3/c1-3-24(32-2)28(36)34-27-22(18-19-31)14-15-23-16-17-25(35(23)30(27)38)29(37)33-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27,32H,3,14-19,31H2,1-2H3,(H,33,37)(H,34,36)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 140n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32599
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H44N6O4/c1-2-29(37)33(43)41-32-27(23-39-36(46)38-22-24-12-6-3-7-13-24)18-19-28-20-21-30(42(28)35(32)45)34(44)40-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32H,2,18-23,37H2,1H3,(H,40,44)(H,41,43)(H2,38,39,46)/t27-,28+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32585
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 12b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](COC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H40N4O5/c1-2-28(36)32(40)38-31-26(22-44-35(43)25-16-10-5-11-17-25)18-19-27-20-21-29(39(27)34(31)42)33(41)37-30(23-12-6-3-7-13-23)24-14-8-4-9-15-24/h3-17,26-31H,2,18-22,36H2,1H3,(H,37,41)(H,38,40)/t26-,27+,28+,29+,31+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32590
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 20a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN(C)Cc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H45N5O3/c1-3-30(37)34(42)39-33-28(24-40(2)23-25-13-7-4-8-14-25)19-20-29-21-22-31(41(29)36(33)44)35(43)38-32(26-15-9-5-10-16-26)27-17-11-6-12-18-27/h4-18,28-33H,3,19-24,37H2,1-2H3,(H,38,43)(H,39,42)/t28-,29+,30+,31+,33+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32593
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)CN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H40N6O4/c1-2-23(32)28(38)35-27-21(18-33-25(37)17-31)13-14-22-15-16-24(36(22)30(27)40)29(39)34-26(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-24,26-27H,2,13-18,31-32H2,1H3,(H,33,37)(H,34,39)(H,35,38)/t21-,22+,23+,24+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32597
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 24b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNS(=O)(=O)c2ccc(C)cc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H43N5O5S/c1-3-29(36)33(41)39-32-26(22-37-46(44,45)28-19-14-23(2)15-20-28)16-17-27-18-21-30(40(27)35(32)43)34(42)38-31(24-10-6-4-7-11-24)25-12-8-5-9-13-25/h4-15,19-20,26-27,29-32,37H,3,16-18,21-22,36H2,1-2H3,(H,38,42)(H,39,41)/t26-,27+,29+,30+,32+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32594
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(C)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H39N5O4/c1-3-24(31)28(37)34-27-22(18-32-19(2)36)14-15-23-16-17-25(35(23)30(27)39)29(38)33-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27H,3,14-18,31H2,1-2H3,(H,32,36)(H,33,38)(H,34,37)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32598
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26a)
Show SMILES CCNC(=O)NC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C31H42N6O4/c1-3-24(32)28(38)36-27-22(19-34-31(41)33-4-2)15-16-23-17-18-25(37(23)30(27)40)29(39)35-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27H,3-4,15-19,32H2,1-2H3,(H,35,39)(H,36,38)(H2,33,34,41)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32581
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 3b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N4O4/c1-3-23(30-2)27(35)32-26-21(18-34)14-15-22-16-17-24(33(22)29(26)37)28(36)31-25(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,21-26,30,34H,3,14-18H2,1-2H3,(H,31,36)(H,32,35)/t21-,22+,23+,24+,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32586
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 14a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](Cn2cc(nn2)[C@H](O)CC)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C33H43N7O4/c1-3-25(34)31(42)36-30-23(19-39-20-26(37-38-39)28(41)4-2)15-16-24-17-18-27(40(24)33(30)44)32(43)35-29(21-11-7-5-8-12-21)22-13-9-6-10-14-22/h5-14,20,23-25,27-30,41H,3-4,15-19,34H2,1-2H3,(H,35,43)(H,36,42)/t23-,24+,25+,27+,28-,30+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32603
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 28b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(N)=S)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N6O3S/c1-2-22(30)26(36)34-25-20(17-32-29(31)39)13-14-21-15-16-23(35(21)28(25)38)27(37)33-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,30H2,1H3,(H,33,37)(H,34,36)(H3,31,32,39)/t20-,21+,22+,23+,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 220n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32581
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 3b)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N4O4/c1-3-23(30-2)27(35)32-26-21(18-34)14-15-22-16-17-24(33(22)29(26)37)28(36)31-25(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,21-26,30,34H,3,14-18H2,1-2H3,(H,31,36)(H,32,35)/t21-,22+,23+,24+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 230n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32599
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H44N6O4/c1-2-29(37)33(43)41-32-27(23-39-36(46)38-22-24-12-6-3-7-13-24)18-19-28-20-21-30(42(28)35(32)45)34(44)40-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32H,2,18-23,37H2,1H3,(H,40,44)(H,41,43)(H2,38,39,46)/t27-,28+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 240n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32596
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 24a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNS(C)(=O)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N5O5S/c1-3-23(30)27(35)33-26-21(18-31-40(2,38)39)14-15-22-16-17-24(34(22)29(26)37)28(36)32-25(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,21-26,31H,3,14-18,30H2,1-2H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32583
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 10a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN=[N+]=[N-])CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H35N7O3/c1-2-22(29)26(36)33-25-20(17-31-34-30)13-14-21-15-16-23(35(21)28(25)38)27(37)32-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,29H2,1H3,(H,32,37)(H,33,36)/t20-,21+,22+,23+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32588
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18a | 1-...)
Show SMILES CCNC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H41N5O3/c1-3-24(31)28(36)34-27-22(19-32-4-2)15-16-23-17-18-25(35(23)30(27)38)29(37)33-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27,32H,3-4,15-19,31H2,1-2H3,(H,33,37)(H,34,36)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 240n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32602
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 28a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(N)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N6O4/c1-2-22(30)26(36)34-25-20(17-32-29(31)39)13-14-21-15-16-23(35(21)28(25)38)27(37)33-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,30H2,1H3,(H,33,37)(H,34,36)(H3,31,32,39)/t20-,21+,22+,23+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32604
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 31a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CC#N)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H35N5O3/c1-2-23(31)27(35)33-26-21(17-18-30)13-14-22-15-16-24(34(22)29(26)37)28(36)32-25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-26H,2,13-17,31H2,1H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM26205
PNG
((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(2-ami...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CCN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N5O3/c1-2-23(31)27(35)33-26-21(17-18-30)13-14-22-15-16-24(34(22)29(26)37)28(36)32-25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-26H,2,13-18,30-31H2,1H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 250n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32595
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22c | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H41N5O4/c1-2-28(36)33(42)39-31-26(22-37-32(41)25-16-10-5-11-17-25)18-19-27-20-21-29(40(27)35(31)44)34(43)38-30(23-12-6-3-7-13-23)24-14-8-4-9-15-24/h3-17,26-31H,2,18-22,36H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t26-,27+,28+,29+,31+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 260n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM26203
PNG
((3S,6S,7S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphe...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H36N4O4/c1-2-22(29)26(34)31-25-20(17-33)13-14-21-15-16-23(32(21)28(25)36)27(35)30-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25,33H,2,13-17,29H2,1H3,(H,30,35)(H,31,34)/t20-,21+,22+,23+,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 270n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32606
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 34a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CCO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N4O4/c1-2-23(30)27(35)32-26-21(17-18-34)13-14-22-15-16-24(33(22)29(26)37)28(36)31-25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-26,34H,2,13-18,30H2,1H3,(H,31,36)(H,32,35)/t21-,22+,23+,24+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 280n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM26203
PNG
((3S,6S,7S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphe...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CO)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H36N4O4/c1-2-22(29)26(34)31-25-20(17-33)13-14-21-15-16-23(32(21)28(25)36)27(35)30-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25,33H,2,13-17,29H2,1H3,(H,30,35)(H,31,34)/t20-,21+,22+,23+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32598
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26a)
Show SMILES CCNC(=O)NC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C31H42N6O4/c1-3-24(32)28(38)36-27-22(19-34-31(41)33-4-2)15-16-23-17-18-25(37(23)30(27)40)29(39)35-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27H,3-4,15-19,32H2,1-2H3,(H,35,39)(H,36,38)(H2,33,34,41)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 300n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32584
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 12a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](COC(C)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H38N4O5/c1-3-24(31)28(36)33-27-22(18-39-19(2)35)14-15-23-16-17-25(34(23)30(27)38)29(37)32-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27H,3,14-18,31H2,1-2H3,(H,32,37)(H,33,36)/t22-,23+,24+,25+,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 320n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32604
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 31a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CC#N)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H35N5O3/c1-2-23(31)27(35)33-26-21(17-18-30)13-14-22-15-16-24(34(22)29(26)37)28(36)32-25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-26H,2,13-17,31H2,1H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 320n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32589
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 18b | 1-...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H43N5O3/c1-2-29(36)33(41)39-32-27(23-37-22-24-12-6-3-7-13-24)18-19-28-20-21-30(40(28)35(32)43)34(42)38-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32,37H,2,18-23,36H2,1H3,(H,38,42)(H,39,41)/t27-,28+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 320n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32594
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(C)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H39N5O4/c1-3-24(31)28(37)34-27-22(18-32-19(2)36)14-15-23-16-17-25(35(23)30(27)39)29(38)33-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27H,3,14-18,31H2,1-2H3,(H,32,36)(H,33,38)(H,34,37)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 330n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32600
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26c)
Show SMILES CCNC(=S)NC[C@H]1CC[C@H]2CC[C@H](N2C(=O)[C@H]1NC(=O)[C@@H](N)CC)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C31H42N6O3S/c1-3-24(32)28(38)36-27-22(19-34-31(41)33-4-2)15-16-23-17-18-25(37(23)30(27)40)29(39)35-26(20-11-7-5-8-12-20)21-13-9-6-10-14-21/h5-14,22-27H,3-4,15-19,32H2,1-2H3,(H,35,39)(H,36,38)(H2,33,34,41)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 330n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32602
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 28a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(N)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H38N6O4/c1-2-22(30)26(36)34-25-20(17-32-29(31)39)13-14-21-15-16-23(35(21)28(25)38)27(37)33-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,30H2,1H3,(H,33,37)(H,34,36)(H3,31,32,39)/t20-,21+,22+,23+,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 340n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM13211
PNG
((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1CCC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C27H34N4O3/c1-2-21(28)25(32)29-22-15-9-14-20-16-17-23(31(20)27(22)34)26(33)30-24(18-10-5-3-6-11-18)19-12-7-4-8-13-19/h3-8,10-13,20-24H,2,9,14-17,28H2,1H3,(H,29,32)(H,30,33)/t20-,21-,22-,23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 360n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32596
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 24a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNS(C)(=O)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C29H39N5O5S/c1-3-23(30)27(35)33-26-21(18-31-40(2,38)39)14-15-22-16-17-24(34(22)29(26)37)28(36)32-25(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,21-26,31H,3,14-18,30H2,1-2H3,(H,32,36)(H,33,35)/t21-,22+,23+,24+,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 360n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32592
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 20c)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN(CC)CC)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C32H45N5O3/c1-4-26(33)30(38)35-29-24(21-36(5-2)6-3)17-18-25-19-20-27(37(25)32(29)40)31(39)34-28(22-13-9-7-10-14-22)23-15-11-8-12-16-23/h7-16,24-29H,4-6,17-21,33H2,1-3H3,(H,34,39)(H,35,38)/t24-,25+,26+,27+,29+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 370n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32586
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 14a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](Cn2cc(nn2)[C@H](O)CC)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C33H43N7O4/c1-3-25(34)31(42)36-30-23(19-39-20-26(37-38-39)28(41)4-2)15-16-24-17-18-27(40(24)33(30)44)32(43)35-29(21-11-7-5-8-12-21)22-13-9-6-10-14-22/h5-14,20,23-25,27-30,41H,3-4,15-19,34H2,1-2H3,(H,35,43)(H,36,42)/t23-,24+,25+,27+,28-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 370n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32601
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 26d)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=S)NCc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H44N6O3S/c1-2-29(37)33(43)41-32-27(23-39-36(46)38-22-24-12-6-3-7-13-24)18-19-28-20-21-30(42(28)35(32)45)34(44)40-31(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,27-32H,2,18-23,37H2,1H3,(H,40,44)(H,41,43)(H2,38,39,46)/t27-,28+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 380n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM32587
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 16a)
Show SMILES [#6]-[#6]-[#6@H](-[#7])-[#6](=O)-[#7]-[#6@H]-1-[#6@@H](-[#6]\[#7]=[#6](\[#7])-[#7])-[#6]-[#6]-[#6@H]-2-[#6]-[#6]-[#6@H](-[#7]-2-[#6]-1=O)-[#6](=O)-[#7]-[#6](-c1ccccc1)-c1ccccc1 |r|
Show InChI InChI=1S/C29H39N7O3/c1-2-22(30)26(37)35-25-20(17-33-29(31)32)13-14-21-15-16-23(36(21)28(25)39)27(38)34-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,30H2,1H3,(H,34,38)(H,35,37)(H4,31,32,33)/t20-,21+,22+,23+,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 390n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32584
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 12a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](COC(C)=O)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H38N4O5/c1-3-24(31)28(36)33-27-22(18-39-19(2)35)14-15-23-16-17-25(34(23)30(27)38)29(37)32-26(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-27H,3,14-18,31H2,1-2H3,(H,32,37)(H,33,36)/t22-,23+,24+,25+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 400n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP


(Homo sapiens (Human))		BDBM13212
PNG
((3S,6S,9aS)-N-(diphenylmethyl)-6-[(2S)-2-(methylam...)
Show SMILES CC[C@H](NC)C(=O)N[C@H]1CCC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H36N4O3/c1-3-22(29-2)26(33)30-23-16-10-15-21-17-18-24(32(21)28(23)35)27(34)31-25(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,21-25,29H,3,10,15-18H2,1-2H3,(H,30,33)(H,31,34)/t21-,22-,23-,24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32593
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 22a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNC(=O)CN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C30H40N6O4/c1-2-23(32)28(38)35-27-21(18-33-25(37)17-31)13-14-22-15-16-24(36(22)30(27)40)29(39)34-26(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,21-24,26-27H,2,13-18,31-32H2,1H3,(H,33,37)(H,34,39)(H,35,38)/t21-,22+,23+,24+,27+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 430n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32591
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 20b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN(CC)Cc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C37H47N5O3/c1-3-31(38)35(43)40-34-29(25-41(4-2)24-26-14-8-5-9-15-26)20-21-30-22-23-32(42(30)37(34)45)36(44)39-33(27-16-10-6-11-17-27)28-18-12-7-13-19-28/h5-19,29-34H,3-4,20-25,38H2,1-2H3,(H,39,44)(H,40,43)/t29-,30+,31+,32+,34+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 440n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32583
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 10a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN=[N+]=[N-])CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H35N7O3/c1-2-22(29)26(36)33-25-20(17-31-34-30)13-14-21-15-16-23(35(21)28(25)38)27(37)32-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,29H2,1H3,(H,32,37)(H,33,36)/t20-,21+,22+,23+,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 450n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32597
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 24b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CNS(=O)(=O)c2ccc(C)cc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H43N5O5S/c1-3-29(36)33(41)39-32-26(22-37-46(44,45)28-19-14-23(2)15-20-28)16-17-27-18-21-30(40(27)35(32)43)34(42)38-31(24-10-6-4-7-11-24)25-12-8-5-9-13-25/h4-15,19-20,26-27,29-32,37H,3,16-18,21-22,36H2,1-2H3,(H,38,42)(H,39,41)/t26-,27+,29+,30+,32+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 510n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32585
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 12b)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](COC(=O)c2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C35H40N4O5/c1-2-28(36)32(40)38-31-26(22-44-35(43)25-16-10-5-11-17-25)18-19-27-20-21-29(39(27)34(31)42)33(41)37-30(23-12-6-3-7-13-23)24-14-8-4-9-15-24/h3-17,26-31H,2,18-22,36H2,1H3,(H,37,41)(H,38,40)/t26-,27+,28+,29+,31+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 600n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32590
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 20a)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN(C)Cc2ccccc2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C36H45N5O3/c1-3-30(37)34(42)39-33-28(24-40(2)23-25-13-7-4-8-14-25)19-20-29-21-22-31(41(29)36(33)44)35(43)38-32(26-15-9-5-10-16-26)27-17-11-6-12-18-27/h4-18,28-33H,3,19-24,37H2,1-2H3,(H,38,43)(H,39,42)/t28-,29+,30+,31+,33+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 650n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM26204
PNG
((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(amino...)
Show SMILES CC[C@H](N)C(=O)N[C@H]1[C@@H](CN)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C28H37N5O3/c1-2-22(30)26(34)32-25-20(17-29)13-14-21-15-16-23(33(21)28(25)36)27(35)31-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,29-30H2,1H3,(H,31,35)(H,32,34)/t20-,21+,22+,23+,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 970n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3


(Homo sapiens (Human))		BDBM32587
PNG
(1-aza-2-oxobicyclo[5.3.0]decane scaffold, 16a)
Show SMILES [#6]-[#6]-[#6@H](-[#7])-[#6](=O)-[#7]-[#6@H]-1-[#6@@H](-[#6]\[#7]=[#6](\[#7])-[#7])-[#6]-[#6]-[#6@H]-2-[#6]-[#6]-[#6@H](-[#7]-2-[#6]-1=O)-[#6](=O)-[#7]-[#6](-c1ccccc1)-c1ccccc1 |r|
Show InChI InChI=1S/C29H39N7O3/c1-2-22(30)26(37)35-25-20(17-33-29(31)32)13-14-21-15-16-23(36(21)28(25)39)27(38)34-24(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-25H,2,13-17,30H2,1H3,(H,34,38)(H,35,37)(H4,31,32,33)/t20-,21+,22+,23+,25+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.40E+3n/an/an/an/a7.523



Universita degli Studi di Milano



Assay Description
Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...

Bioorg Med Chem 17: 5834-56 (2009)


Article DOI: 10.1016/j.bmc.2009.07.009
BindingDB Entry DOI: 10.7270/Q28W3BNV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%