Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415053
(CHEMBL583457)Show SMILES CC(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H17Cl3N4O3S2/c1-12(13-5-8-16(24)17(25)9-13)11-26-22(30)15-7-6-14(23)10-19(15)29-34(31,32)20-4-2-3-18-21(20)28-33-27-18/h2-10,12,29H,11H2,1H3,(H,26,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415066
(CHEMBL585914)Show SMILES OC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H15Cl3N4O5S2/c23-12-5-6-13(21(30)26-18(22(31)32)9-11-4-7-14(24)15(25)8-11)17(10-12)29-36(33,34)19-3-1-2-16-20(19)28-35-27-16/h1-8,10,18,29H,9H2,(H,26,30)(H,31,32)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415058
(CHEMBL571206)Show SMILES C[C@@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)[C@@H](O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C22H18BrClN4O4S2/c1-12(21(29)13-4-2-5-14(23)10-13)25-22(30)16-9-8-15(24)11-18(16)28-34(31,32)19-7-3-6-17-20(19)27-33-26-17/h2-12,21,28-29H,1H3,(H,25,30)/t12-,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415052
(CHEMBL583343)Show SMILES Clc1ccc(cc1)C(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H19Cl3N4O3S2/c28-18-8-4-16(5-9-18)22(17-6-10-19(29)11-7-17)15-31-27(35)21-13-12-20(30)14-24(21)34-39(36,37)25-3-1-2-23-26(25)33-38-32-23/h1-14,22,34H,15H2,(H,31,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415068
(CHEMBL569470)Show SMILES OC(=O)[C@H](Cc1ccc(Cl)c(Br)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H15BrCl2N4O5S2/c23-14-8-11(4-7-15(14)25)9-18(22(31)32)26-21(30)13-6-5-12(24)10-17(13)29-36(33,34)19-3-1-2-16-20(19)28-35-27-16/h1-8,10,18,29H,9H2,(H,26,30)(H,31,32)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415072
(CHEMBL565511)Show SMILES CC(C)(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20Cl2N4O3S2/c1-23(2,14-6-8-15(24)9-7-14)13-26-22(30)17-11-10-16(25)12-19(17)29-34(31,32)20-5-3-4-18-21(20)28-33-27-18/h3-12,29H,13H2,1-2H3,(H,26,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415074
(CHEMBL566604)Show SMILES C[C@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccccc1 |r| Show InChI InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 63.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415064
(CHEMBL584259)Show SMILES OC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H16Cl2N4O5S2/c23-13-6-4-12(5-7-13)10-18(22(30)31)25-21(29)15-9-8-14(24)11-17(15)28-35(32,33)19-3-1-2-16-20(19)27-34-26-16/h1-9,11,18,28H,10H2,(H,25,29)(H,30,31)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 63.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415061
(CHEMBL570521)Show SMILES Clc1ccc(C(=O)NCCc2ccc(Cl)c(Cl)c2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C21H15Cl3N4O3S2/c22-13-5-6-14(21(29)25-9-8-12-4-7-15(23)16(24)10-12)18(11-13)28-33(30,31)19-3-1-2-17-20(19)27-32-26-17/h1-7,10-11,28H,8-9H2,(H,25,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415067
(CHEMBL566359)Show SMILES OC(=O)[C@@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H15Cl3N4O5S2/c23-12-5-6-13(21(30)26-18(22(31)32)9-11-4-7-14(24)15(25)8-11)17(10-12)29-36(33,34)19-3-1-2-16-20(19)28-35-27-16/h1-8,10,18,29H,9H2,(H,26,30)(H,31,32)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415062
(CHEMBL566390)Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H17ClN4O5S2/c23-14-9-10-15(21(28)24-18(22(29)30)11-13-5-2-1-3-6-13)17(12-14)27-34(31,32)19-8-4-7-16-20(19)26-33-25-16/h1-10,12,18,27H,11H2,(H,24,28)(H,29,30)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415051
(CHEMBL584063)Show SMILES C[C@@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccccc1 |r| Show InChI InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415051
(CHEMBL584063)Show SMILES C[C@@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccccc1 |r| Show InChI InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415071
(CHEMBL566360)Show SMILES CC(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H18Cl2N4O3S2/c1-13(14-5-7-15(23)8-6-14)12-25-22(29)17-10-9-16(24)11-19(17)28-33(30,31)20-4-2-3-18-21(20)27-32-26-18/h2-11,13,28H,12H2,1H3,(H,25,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415059
(CHEMBL569616)Show SMILES Clc1ccc(C(=O)NCCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C21H17ClN4O3S2/c22-15-9-10-16(21(27)23-12-11-14-5-2-1-3-6-14)18(13-15)26-31(28,29)19-8-4-7-17-20(19)25-30-24-17/h1-10,13,26H,11-12H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415063
(CHEMBL570518)Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H17ClN4O5S2/c23-14-9-10-15(21(28)24-18(22(29)30)11-13-5-2-1-3-6-13)17(12-14)27-34(31,32)19-8-4-7-16-20(19)26-33-25-16/h1-10,12,18,27H,11H2,(H,24,28)(H,29,30)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415054
(CHEMBL570297)Show SMILES C[C@@H]([C@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C23H17Cl3N4O5S2/c1-11(12-5-8-15(25)16(26)9-12)20(23(32)33)27-22(31)14-7-6-13(24)10-18(14)30-37(34,35)19-4-2-3-17-21(19)29-36-28-17/h2-11,20,30H,1H3,(H,27,31)(H,32,33)/t11-,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415055
(CHEMBL569849)Show SMILES C[C@@H]([C@@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C23H17Cl3N4O5S2/c1-11(12-5-8-15(25)16(26)9-12)20(23(32)33)27-22(31)14-7-6-13(24)10-18(14)30-37(34,35)19-4-2-3-17-21(19)29-36-28-17/h2-11,20,30H,1H3,(H,27,31)(H,32,33)/t11-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415068
(CHEMBL569470)Show SMILES OC(=O)[C@H](Cc1ccc(Cl)c(Br)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H15BrCl2N4O5S2/c23-14-8-11(4-7-15(14)25)9-18(22(31)32)26-21(30)13-6-5-12(24)10-17(13)29-36(33,34)19-3-1-2-16-20(19)28-35-27-16/h1-8,10,18,29H,9H2,(H,26,30)(H,31,32)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415066
(CHEMBL585914)Show SMILES OC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H15Cl3N4O5S2/c23-12-5-6-13(21(30)26-18(22(31)32)9-11-4-7-14(24)15(25)8-11)17(10-12)29-36(33,34)19-3-1-2-16-20(19)28-35-27-16/h1-8,10,18,29H,9H2,(H,26,30)(H,31,32)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415065
(CHEMBL569848)Show SMILES OC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H16Cl2N4O5S2/c23-13-6-4-12(5-7-13)10-18(22(30)31)25-21(29)15-9-8-14(24)11-17(15)28-35(32,33)19-3-1-2-16-20(19)27-34-26-16/h1-9,11,18,28H,10H2,(H,25,29)(H,30,31)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415070
(CHEMBL571832)Show SMILES CN(CCc1ccccc1)C(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 Show InChI InChI=1S/C22H19ClN4O3S2/c1-27(13-12-15-6-3-2-4-7-15)22(28)17-11-10-16(23)14-19(17)26-32(29,30)20-9-5-8-18-21(20)25-31-24-18/h2-11,14,26H,12-13H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415071
(CHEMBL566360)Show SMILES CC(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H18Cl2N4O3S2/c1-13(14-5-7-15(23)8-6-14)12-25-22(29)17-10-9-16(24)11-19(17)28-33(30,31)20-4-2-3-18-21(20)27-32-26-18/h2-11,13,28H,12H2,1H3,(H,25,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415073
(CHEMBL565325)Show SMILES Brc1ccc(C(=O)NCCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C21H17BrN4O3S2/c22-15-9-10-16(21(27)23-12-11-14-5-2-1-3-6-14)18(13-15)26-31(28,29)19-8-4-7-17-20(19)25-30-24-17/h1-10,13,26H,11-12H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415074
(CHEMBL566604)Show SMILES C[C@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccccc1 |r| Show InChI InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415067
(CHEMBL566359)Show SMILES OC(=O)[C@@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H15Cl3N4O5S2/c23-12-5-6-13(21(30)26-18(22(31)32)9-11-4-7-14(24)15(25)8-11)17(10-12)29-36(33,34)19-3-1-2-16-20(19)28-35-27-16/h1-8,10,18,29H,9H2,(H,26,30)(H,31,32)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415053
(CHEMBL583457)Show SMILES CC(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H17Cl3N4O3S2/c1-12(13-5-8-16(24)17(25)9-13)11-26-22(30)15-7-6-14(23)10-19(15)29-34(31,32)20-4-2-3-18-21(20)28-33-27-18/h2-10,12,29H,11H2,1H3,(H,26,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415054
(CHEMBL570297)Show SMILES C[C@@H]([C@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C23H17Cl3N4O5S2/c1-11(12-5-8-15(25)16(26)9-12)20(23(32)33)27-22(31)14-7-6-13(24)10-18(14)30-37(34,35)19-4-2-3-17-21(19)29-36-28-17/h2-11,20,30H,1H3,(H,27,31)(H,32,33)/t11-,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415051
(CHEMBL584063)Show SMILES C[C@@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccccc1 |r| Show InChI InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415073
(CHEMBL565325)Show SMILES Brc1ccc(C(=O)NCCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C21H17BrN4O3S2/c22-15-9-10-16(21(27)23-12-11-14-5-2-1-3-6-14)18(13-15)26-31(28,29)19-8-4-7-17-20(19)25-30-24-17/h1-10,13,26H,11-12H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415065
(CHEMBL569848)Show SMILES OC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H16Cl2N4O5S2/c23-13-6-4-12(5-7-13)10-18(22(30)31)25-21(29)15-9-8-14(24)11-17(15)28-35(32,33)19-3-1-2-16-20(19)27-34-26-16/h1-9,11,18,28H,10H2,(H,25,29)(H,30,31)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415056
(CHEMBL570761)Show SMILES CC(C)([C@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C24H20Cl2N4O5S2/c1-24(2,13-6-8-14(25)9-7-13)21(23(32)33)27-22(31)16-11-10-15(26)12-18(16)30-37(34,35)19-5-3-4-17-20(19)29-36-28-17/h3-12,21,30H,1-2H3,(H,27,31)(H,32,33)/t21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415069
(CHEMBL572046)Show SMILES Clc1ccc(C(=O)NCCCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C22H19ClN4O3S2/c23-16-11-12-17(22(28)24-13-5-8-15-6-2-1-3-7-15)19(14-16)27-32(29,30)20-10-4-9-18-21(20)26-31-25-18/h1-4,6-7,9-12,14,27H,5,8,13H2,(H,24,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415060
(CHEMBL571457)Show SMILES Clc1ccc(CCNC(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cccc3nsnc23)cc1 Show InChI InChI=1S/C21H16Cl2N4O3S2/c22-14-6-4-13(5-7-14)10-11-24-21(28)16-9-8-15(23)12-18(16)27-32(29,30)19-3-1-2-17-20(19)26-31-25-17/h1-9,12,27H,10-11H2,(H,24,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415057
(CHEMBL569018)Show SMILES OC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C28H19Cl3N4O5S2/c29-17-8-4-15(5-9-17)24(16-6-10-18(30)11-7-16)26(28(37)38)32-27(36)20-13-12-19(31)14-22(20)35-42(39,40)23-3-1-2-21-25(23)34-41-33-21/h1-14,24,26,35H,(H,32,36)(H,37,38)/t26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415058
(CHEMBL571206)Show SMILES C[C@@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)[C@@H](O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C22H18BrClN4O4S2/c1-12(21(29)13-4-2-5-14(23)10-13)25-22(30)16-9-8-15(24)11-18(16)28-34(31,32)19-7-3-6-17-20(19)27-33-26-17/h2-12,21,28-29H,1H3,(H,25,30)/t12-,21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415055
(CHEMBL569849)Show SMILES C[C@@H]([C@@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C23H17Cl3N4O5S2/c1-11(12-5-8-15(25)16(26)9-12)20(23(32)33)27-22(31)14-7-6-13(24)10-18(14)30-37(34,35)19-4-2-3-17-21(19)29-36-28-17/h2-11,20,30H,1H3,(H,27,31)(H,32,33)/t11-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415051
(CHEMBL584063)Show SMILES C[C@@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccccc1 |r| Show InChI InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415064
(CHEMBL584259)Show SMILES OC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H16Cl2N4O5S2/c23-13-6-4-12(5-7-13)10-18(22(30)31)25-21(29)15-9-8-14(24)11-17(15)28-35(32,33)19-3-1-2-16-20(19)27-34-26-16/h1-9,11,18,28H,10H2,(H,25,29)(H,30,31)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415069
(CHEMBL572046)Show SMILES Clc1ccc(C(=O)NCCCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C22H19ClN4O3S2/c23-16-11-12-17(22(28)24-13-5-8-15-6-2-1-3-7-15)19(14-16)27-32(29,30)20-10-4-9-18-21(20)26-31-25-18/h1-4,6-7,9-12,14,27H,5,8,13H2,(H,24,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50196205
(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-N-ben...)Show SMILES Clc1ccc(C(=O)NCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C20H15ClN4O3S2/c21-14-9-10-15(20(26)22-12-13-5-2-1-3-6-13)17(11-14)25-30(27,28)18-8-4-7-16-19(18)24-29-23-16/h1-11,25H,12H2,(H,22,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415063
(CHEMBL570518)Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H17ClN4O5S2/c23-14-9-10-15(21(28)24-18(22(29)30)11-13-5-2-1-3-6-13)17(12-14)27-34(31,32)19-8-4-7-16-20(19)26-33-25-16/h1-10,12,18,27H,11H2,(H,24,28)(H,29,30)/t18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415062
(CHEMBL566390)Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 |r| Show InChI InChI=1S/C22H17ClN4O5S2/c23-14-9-10-15(21(28)24-18(22(29)30)11-13-5-2-1-3-6-13)17(12-14)27-34(31,32)19-8-4-7-16-20(19)26-33-25-16/h1-10,12,18,27H,11H2,(H,24,28)(H,29,30)/t18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415056
(CHEMBL570761)Show SMILES CC(C)([C@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C24H20Cl2N4O5S2/c1-24(2,13-6-8-14(25)9-7-13)21(23(32)33)27-22(31)16-11-10-15(26)12-18(16)30-37(34,35)19-5-3-4-17-20(19)29-36-28-17/h3-12,21,30H,1-2H3,(H,27,31)(H,32,33)/t21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415070
(CHEMBL571832)Show SMILES CN(CCc1ccccc1)C(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 Show InChI InChI=1S/C22H19ClN4O3S2/c1-27(13-12-15-6-3-2-4-7-15)22(28)17-11-10-16(23)14-19(17)26-32(29,30)20-9-5-8-18-21(20)25-31-24-18/h2-11,14,26H,12-13H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415059
(CHEMBL569616)Show SMILES Clc1ccc(C(=O)NCCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C21H17ClN4O3S2/c22-15-9-10-16(21(27)23-12-11-14-5-2-1-3-6-14)18(13-15)26-31(28,29)19-8-4-7-17-20(19)25-30-24-17/h1-10,13,26H,11-12H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415061
(CHEMBL570521)Show SMILES Clc1ccc(C(=O)NCCc2ccc(Cl)c(Cl)c2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C21H15Cl3N4O3S2/c22-13-5-6-14(21(29)25-9-8-12-4-7-15(23)16(24)10-12)18(11-13)28-33(30,31)19-3-1-2-17-20(19)27-32-26-17/h1-7,10-11,28H,8-9H2,(H,25,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415072
(CHEMBL565511)Show SMILES CC(C)(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20Cl2N4O3S2/c1-23(2,14-6-8-15(24)9-7-14)13-26-22(30)17-11-10-16(25)12-19(17)29-34(31,32)20-5-3-4-18-21(20)28-33-27-18/h3-12,29H,13H2,1-2H3,(H,26,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415060
(CHEMBL571457)Show SMILES Clc1ccc(CCNC(=O)c2ccc(Cl)cc2NS(=O)(=O)c2cccc3nsnc23)cc1 Show InChI InChI=1S/C21H16Cl2N4O3S2/c22-14-6-4-13(5-7-14)10-11-24-21(28)16-9-8-15(23)12-18(16)27-32(29,30)19-3-1-2-17-20(19)26-31-25-17/h1-9,12,27H,10-11H2,(H,24,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50196205
(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-N-ben...)Show SMILES Clc1ccc(C(=O)NCc2ccccc2)c(NS(=O)(=O)c2cccc3nsnc23)c1 Show InChI InChI=1S/C20H15ClN4O3S2/c21-14-9-10-15(20(26)22-12-13-5-2-1-3-6-13)17(11-14)25-30(27,28)18-8-4-7-16-19(18)24-29-23-16/h1-11,25H,12H2,(H,22,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50415052
(CHEMBL583343)Show SMILES Clc1ccc(cc1)C(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H19Cl3N4O3S2/c28-18-8-4-16(5-9-18)22(17-6-10-19(29)11-7-17)15-31-27(35)21-13-12-20(30)14-24(21)34-39(36,37)25-3-1-2-23-26(25)33-38-32-23/h1-14,22,34H,15H2,(H,31,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK2R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A
(Homo sapiens (Human)) | BDBM50415057
(CHEMBL569018)Show SMILES OC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C28H19Cl3N4O5S2/c29-17-8-4-15(5-9-17)24(16-6-10-18(30)11-7-16)26(28(37)38)32-27(36)20-13-12-19(31)14-22(20)35-42(39,40)23-3-1-2-21-25(23)34-41-33-21/h1-14,24,26,35H,(H,32,36)(H,37,38)/t26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [125I]-CCK-8S from CCK1R after 100 mins by liquid scintillation counting |
Bioorg Med Chem Lett 19: 6373-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.064
BindingDB Entry DOI: 10.7270/Q2222W1W |
More data for this
Ligand-Target Pair | |
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