Affinity Data by PubMed id=19819694

PubMed code 19819694

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50302906 (CHEMBL569227 \| methyl 2-(2-(2-imino-4-oxothiazolid...) Show SMILES COC(=O)c1c(C)c(C)sc1NC(=O)Cc1sc(N)nc1O Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human SFRP1 transfected in human U20S cells by TCF-luciferase reporter gene assay				Bioorg Med Chem Lett 19: 6337-9 (2009) Article DOI: 10.1016/j.bmcl.2009.09.085 BindingDB Entry DOI: 10.7270/Q2930T7H
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50302906 (CHEMBL569227 \| methyl 2-(2-(2-imino-4-oxothiazolid...) Show SMILES COC(=O)c1c(C)c(C)sc1NC(=O)Cc1sc(N)nc1O Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to human SFRP1 by fluorescence spectroscopy				Bioorg Med Chem Lett 19: 6337-9 (2009) Article DOI: 10.1016/j.bmcl.2009.09.085 BindingDB Entry DOI: 10.7270/Q2930T7H
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%