Affinity Data by PubMed id=19874209

PubMed code 19874209

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233049 (2-[2-(6-Chloropyrrolo[2,3-b]pyridin-1-yl)ethyl]dec...) Show SMILES Clc1ccc2ccn(CCN3CCCN4CCCCC4C3)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233048 (2-[2-(6-Bromopyrrolo[2,3-b]pyridin-1-yl)ethyl]deca...) Show SMILES Brc1ccc2ccn(CCN3CCCN4CCCCC4C3)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	492	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233045 (2-[2-(7-Chloropyrrolo[2,3-c]pyridin-1-yl)ethyl]dec...) Show SMILES Clc1nccc2ccn(CCN3CCCN4CCCCC4C3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233046 (2-[(2-Pyrrolo[2,3-c]pyridin-1-yl)ethyl]decahydropy...) Show SMILES C(Cn1ccc2ccncc12)N1CCCN2CCCCC2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM233046 (2-[(2-Pyrrolo[2,3-c]pyridin-1-yl)ethyl]decahydropy...) Show SMILES C(Cn1ccc2ccncc12)N1CCCN2CCCCC2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233044 (2-(2-Pyrrolo[2,3-b]pyridin-1-ylethyl)decahydropyri...) Show SMILES C(Cn1ccc2cccnc12)N1CCCN2CCCCC2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM233048 (2-[2-(6-Bromopyrrolo[2,3-b]pyridin-1-yl)ethyl]deca...) Show SMILES Brc1ccc2ccn(CCN3CCCN4CCCCC4C3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM233049 (2-[2-(6-Chloropyrrolo[2,3-b]pyridin-1-yl)ethyl]dec...) Show SMILES Clc1ccc2ccn(CCN3CCCN4CCCCC4C3)c2n1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM233045 (2-[2-(7-Chloropyrrolo[2,3-c]pyridin-1-yl)ethyl]dec...) Show SMILES Clc1nccc2ccn(CCN3CCCN4CCCCC4C3)c12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233047 (1-[2-(Octahydropyrido[1,2-a][1,4]diazepin-2-yl)eth...) Show SMILES O=c1[nH]c2ccccc2n1CCN1CCCN2CCCCC2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM233044 (2-(2-Pyrrolo[2,3-b]pyridin-1-ylethyl)decahydropyri...) Show SMILES C(Cn1ccc2cccnc12)N1CCCN2CCCCC2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orl�ans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
University of Orl�ans					More data for this Ligand-Target Pair

* indicates data uncertainty>20%